Vitamin D and bone density, fractures, and falls: the end of the story?J Chris Gallagher a
Working with partners in Mongolia, a setting with a particularly high fracture burden and where vitamin D deficiency is highly prevalent, researchers from Queen Mary and Harvard conducted a clinical trial to determine if vitamin D supplementation would decrease risk ofbone fracturesor increase bone str...
Vitamin D status and bone turnover marker levels in Greek women with fragility hip fracture Author(s): Efstathios Drampalos, Lazaros Oikonomidis, Jeremy Oakley, Ioannis Michos and Efstathios Chronopoulos Abstract: There is little data regarding Vitamin D deficiency in Greece. Also conflicting are ...
Vitamin D supplementation does not prevent fractures or falls, or have clinically meaningful effects on bone mineral density, according to the research, which analyzed data from 81 randomized controlled trials -- involving 53,537 people -- that studied the efficacy of over-the-counter supplements. ...
1,2 In animals, retinoic acid suppresses osteoblast activity,3 stimulates osteoclast formation,4 and antagonizes the ability of vitamin D to maintain normal serum calcium levels,5 all of which may contribute to the accelerated bone resorption and fractures observed with hypervitaminosis A.6 In ...
D and bone mineral density and osteoporosis are still controversial while new evidence suggests that Vit. D may play a role in other bone conditions such as osteoarthritis and stress fractures. In order to maintain a ???good bone health??? guidelines concerning the recommended dietary intakes ...
Vitamin D deficiency is a candidate risk factor for osteoporosis, characterized by decreased bone mineral density (BMD). We performed this two-sample Mendelian randomization (MR) analysis to investigate the causal effect of vitamin D on BMD. We extracted 143 single-nucleotide polymorphisms from a re...
Vitamin D deficiency leads to secondary hyperparathyroidism initially and then to mild osteomalacia, both of which conditions may be aymptomatic and may predispose to bone fracture. To assess the importance of vitamin D deficiency in predisposing to fractured neck of femur, we studied the vitamin ...
All data considered, this chapter summarizes the compelling dual benefit of vitamin D on fracture reduction by its bone and muscle target, a concept that is reviewed at the onset of the chapter. 展开 关键词: Vitamin D Falls Muscle strength Bone density Fractures 25-hydroxyvitamin D Osteoporosis...
Taking vitamin D supplements did not significantly reduce the risk of fractures among adults in midlife and older adults, compared with placebo, according to results from an ancillary study of the Vitamin D and Omega-3 Trial (VITAL). Dr Meryl LeBoff The data showed that taking 2000 IU of ...