The goal of this article is to examine the role of metformin in cobalamin deficiency, as well as outline the steps that are necessary to assess the incidence of B12 deficiency and its potential reversal with calcium supplementation in a clinical setting....
After six months of rehabilitation, he could walk independently with a stick but there was persistent lower-limb ataxia and sensory deficits (with residual high T2 signal). This patient had multiple risk factors for developing B12 deficiency: vegetarianism, age, diabetes mellitus and Metformin use....
MetforminVitamin B12Metformin therapy has been associated with vitaminB (VB12) deficiency, but information regarding this adverse effect in Asian populations is limited. We have now examined the relationship between metformin use and VB12 status in individuals with type2 diabetes mellitus in Japan....
Metformin: Vitamin B12 deficiency and peripheral neuropathy: case report
We conducted this study to determine the prevalence of vit B12 deficiency in T2DM patients, the effect of metformin therapy on vit B 12 levels, and the effect of vit B12 deficiency on neuropathy; because vit-B12-induced neuropathy is a treatable condition that may be confused with diabetic ...
Metformin(Glucophage), taken for diabetes Colchicine, taken for gout Some chemotherapy drugs, especially methotrexate Vitamin B12 and vegan diet If you follow avegandiet (meaning you don't eat any animal products, including meat, milk, cheese, and eggs) or you're a vegetarian who doesn't eat...
We report two cases who had symptomatic vitamin B12 deficiency related to metformin use; the mechanisms are discussed. The clinician must be aware of the possibility of metformin-associated B12 deficiency in users who suffer cognitive impairment, peripheral neuropathy, subacute combined degeneration of ...
Our companion article outlines how metformin use can lead to a clinically significant deficiency in vitamin B12, and describes the problems this can cause. In this comment, we outline a project conducted in four primary care practices that aimed to improve metformin-relat...
Likewise there was no correlation observed in the MCV level and vitamin B12 deficiency states. However, PN was documented in 7% of the normal, 23% in low normal and 77% in defiency state. DISCUSSION: 40% of our patients on metformin had low normal or deficient in B12....
Metformin and vitamin B12 deficiency Comment on Tidsskr Nor Laegeforen. 2007 Jan 4;127(1):65. JS Scozzari - 《Archives of Internal Medicine》 被引量: 89发表: 2002年 Miglitol, an α-glucosidase inhibitor, prevents the metformin-induced fall in serum folate and vitamin B12 in subjects with ...