Vitamin B12Thrombotic microangiopathies (TMA) are characterized by microangiopathic hemolytic anemia, thrombocytopenia and organ damage resulting from mechanical factors, accumulation of the ultra-large von Willebrand factor multimers or complement-mediated abnormalities. Severe acquired vitamin B12 (Cobalamin...
among other changes, by a decrease in liver pyridine nucleotides which are of major importance in phosphate uptake during electron transport to molecular oxygen3. The pronounced lowering of liver and its mitochondrial vitamin B12in hyperthyroidism4as well...
VITAMIN B12 AND PROTEIN SYNTHESIS Therefore, vitamins need to be taken from nutrients and supplements daily. They play an important role in carbohydrate, fat and protein metabolism, healthy... None - 《Nutrition Reviews》 被引量: 1发表: 1958年 Vitamin B12 metabolism in eukaryotes. Vitamin B12 ...
1. 1. Vitamin B 12 levels were determined in centipede, millipede, spider, isopod, leech, earthworm, tubifex worm, snail, clam and shrimp. All contained appreciable amounts of vitamin B 12, which ranged from 19 to 4013 pg/mg dry wt. 2. 2. The metabolism of (2- 14C)propionate was ...
The treatment of all inborn errors of Cbl metabolism is parenteral Cbl-OH in doses necessary to maintain biochemical and haematological normality. In addition, dietary measures, folinic acid, betaine and methionine may be necessary in some disorders of intracellular utilisation of Cbl. Prognosis ...
Vitamin B12 (B12; also known as cobalamin) is a B vitamin that has an important role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial metabolism. Clinical B12 deficiency with classic haematological and neurological manifestations is relatively uncommon. However, subclinica...
Multiple sclerosis and vitamin B12 metabolism a new clue Multiple sclerosis (MS) is occasionally associated with vitamin B12 deficiency. Recent studies have shown and increase risk of macrocytosis, low serum and/... E Reynolds,J Linnell 被引量: 0发表: 1988年 Vitamin B12, folic acid, and the...
Hematology and Nutrition Laboratory, Department of Pediatrics New York Medical College, New York, N. Y.John Wiley & Sons, Ltd (10.1111)Annals of the New York Academy of SciencesLuhby AL, Cooperman JM, Lopez R, Giorgia AJ: Vitamin B12 metabolism in thalassemia major. Annals of New York ...
Metformin interferes with vitamin B12 absorption and metabolism. This case illustrates an 87 year-old previously-independent man presenting with progressive gait unsteadiness over one week (assistance of two for transfers) and ascending numbness of the feet (like "walking on ice"). He had a ...
Vitamin B12 is essential for energy metabolism, nerve health, red blood cell formation, and immune function as well as cognitive and cardiovascular health. Unfortunately, due to low stomach acid and genetic differences, many people have difficulty absorbing and using cyanocobalamin, the common form of...