Silymarin has been used for improving hepatic damage and lipid disorders, but its action mechanism remains to be clarified. Here, we investigate the contributions of the gut microbiota to the improvement of liver lipid metabolism by silymarin. We find i)
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Further information on research design is available in theNature Portfolio Reporting Summarylinked to this article. Data availability Gut microbiome and liver transcriptome data were deposited at China NGDC Genome Sequence Archive (https://ngdc.cncb.ac.cn) with access numbersCRA008527andCRA008528, resp...
Jean-Loup PennaforteEmmanuel AndrèsElsevier B.V.European Journal of Internal MedicineZulfiqar AA, Sebaux A, Drame M, Pennaforte JL, Novella JL, et al. (2015) Hypervitaminemia B12 in elderly patients: Frequency and nature of the associated or linked conditions. Preliminary results of a study ...
The main reason was the exploratory nature of the present work. The strengths of the study are the novelty of the systematic approach in terms of search and data extraction, the evaluation of confounding factors, and the evidence gradient that underlines the need for further research. 5. ...
This shows that the nature of their expression changes depending on the nature of the diet and light exposure, and the two receptors may take turns carrying out their functions. The link between darkness and the mode of action of the receptors would be an interesting area of research. The ...