Vitamin B 12 Deficiency组胺H2拮抗剂降血糖药二甲双胍维生素B12缺乏SIR-Liu et al. highlighted an important point, which is well described with regard to metformin therapy . Interestingly, they have categorically stated that: These two patients had B12 deficiency associated with metformin therapy'. ...
Association of biochemical [B.sub.12] deficiency with metformin therapy and vitamin [B.sub.12] supplements: the National Health and Nutrition Examination Survey, 1999-2006 To describe the prevalence of biochemical B(12) deficiency in adults with type 2 diabetes taking metformin compared with those...
Vitamin B12 Supplements Your doctor will advise vitamin B12 supplements if your B12 levels are low but not severe. These are available at the drugstore on their own or as part of a B-complex vitamin or a multivitamin.You can buy the supplements to swallow as pills, to dissolve under your...
Vitamin B12 deficiency may result from chronic use of proton pump inhibitors, use of metformin, B12 absorption abnormalities in the stomach and upper gut, or by a true vegan diet where B12 supplementation is not provided. Answers to questions about arthroscopic surgery, vitamin B12, and hernia re...
Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial ObjectivesTo study the effects of metformin on the incidence of vitamin B-12 deficiency (<150 pmol/l), low concentrations of vitamin B-12 (150-220 pmol...
Metformin - members with vitamin B-12 deficiency due to use of metformin that is not corrected by oral vitamin B-12; or Methylmalonic aciduria; or Tobacco Amblyopia - retrobulbar neuritis associated with heavy smoking, also known as tobacco amblyopia. Physician administration of intramuscular or subc...
Andres E, Noel E, Goichot B: Metformin-associated vitamin B12 deficiency. Arch Intern Med. 2002 Oct 28;162(19):2251-2. [Article] Gilligan MA: Metformin and vitamin B12 deficiency. Arch Intern Med. 2002 Feb 25;162(4):484-5. [Article] Bonaa KH, Njolstad I, Ueland PM, Schirmer ...
Biemans, E.et al. Cobalamin status and its relation with depression, cognition and neuropathy in patients with type 2 diabetes mellitus using metformin.Acta Diabetol.52, 383–393 (2015). Google Scholar Clarke, R.et al. Low vitamin B-12 status and risk of cognitive decline in older adults....
Long-term use of metformin is associated with malabsorption of vitam... DJ Wile,C Toth - 《Diabetes Care》 被引量: 373发表: 2010年 Malabsorption of vitamin B 12 and intrinsic factor secretion during biguanide therapy In a survey of 46 randomly selected diabetic patients on biguanide therapy, ...
This deficiency did not correlate with either the duration of metformin use or an abnormal MCV. The number of patient with PN in the B-12 deficiency group was surprising. We recognized that the diagnosis of PN was rarely rigorously defined in our patients; but suspect that ...