A third mechanism of vitC-associated action could be on the cholinergic response of vascular smooth muscle cells (VSMCs). Increased oxidative stress has been found to reduce muscarinic receptor function in smooth muscle cells of the urinary bladder [19], and studies have shown an attenuated ...
Thus, the results indicate that LCA is a selective VDR ligand acting in the lower intestine, particularly the ileum. LCA may be a signaling molecule, which links intestinal bacteria and host VDR function. Keywords: vitamin D receptor; vitamin D; lithocholic acid; bile acid; CYP24A1; TRPV6;...
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