Because the subunits are not exactly equivalent, Papillomaviridae, Polyomaviridae, as well as poliovirus, have “pseudo-triangulation numbers” so are referred to as P = 7, P = 7, and P = 3 symmetries respectiv
Bacteriophages have important roles in the ecology of the human gut microbiome but are under-represented in reference databases. To address this problem, we assembled the Metagenomic Gut Virus catalogue that comprises 189,680 viral genomes from 11,810 publicly available human stool metagenomes. Over ...
DNA viruses have a major influence on the ecology and evolution of cellular organisms1234, but their overall diversity and evolutionary trajectories remain elusive5. Here we carried out a phylogeny-guided genome-resolved metagenomic survey of the sunlit oceans and discovered plankton-infecting relatives ...
While neutrophils respond rapidly, they have a short-life span (1–2 days) and are unable to perform phagocytosis repeatedly. Following pathogen extermination, neutrophils self-destruct in a natural process referred to as apoptosis. Macrophages (15–30 µm), on the other hand, are long-lived...
both have the potential for outbreaks in local areas of China. Our study can help to promote the understanding of risk distribution and disease burden ofBunyaviralesviruses in China, and the risk maps of CCHFV and RVFV occurrence are crucial to the targeted surveillance and control, especially ...
An increasing number of plant viruses and viroids have been reported from all over the world due largely to metavirogenomics approaches with technological
Seasonal trends, possibly related to epidemic infections, have been described in the diagnosis or relapse of Graves' disease with higher rates in spring and summer [41,42]. Geographical differences have also been described in England in the incidence of Grave's disease which could be an indirect...
The discovery of giant viruses with genome and physical size comparable to cellular organisms, remnants of protein translation machinery and virus-specific parasites (virophages) have raised intriguing questions about their origin. Evidence advocates for their inclusion into global phylogenomic studies and...
low coverage (the latter sequences were not deposited to GenBank). Complete genomes were assembled for all viruses, except for the clades 1 and 2 of leishbuviruses, in which the middle segments were not found. These glycoprotein-coding segments usually have an order of magnitude lower coverage...
Some of these viruses have important biological roles, such as limiting fungal pathogenicity4,5 or increasing protist fecundity6. The double-stranded RNA (dsRNA) viruses of the family Totiviridae have evolved extensive diversity and are present in phyla separated by a billion years of evolution,...