Prophylactic VLP (Virus-like Particle) vaccine for cervical carcinoma本发明公开了一种宫颈癌预防性VLP疫苗,VLP是HPV18型,52型,58型L1蛋白的环部位插入1个16型的E7表位而得到的嵌合蛋白的聚集体. The present invention discloses a cervical cancer preventive VLP vaccine, VLP is HPV18, 52, 58 type L1 ...
virus-like particle vaccine by intranasal vaccination elicits protective immunity against 系统标签: virus syncytial intranasal viral vaccine respiratory ActaBiochimBiophysSin,2017,49(1),74–82doi:10.1093/abbs/gmw118AdvanceAccessPublicationDate:14December2016OriginalArticleOriginalArticleVirus-likeparticlevaccineby...
病毒样颗粒(Virus like particle, VLP)是由一个或多个具有自组装能力的不同分子组成的病毒衍生结构。它在结构上模仿病毒颗粒的形状和大小,但缺乏遗传物质,因此无法感染宿主细胞。病毒结构蛋白的表达和自组装可以在各种活的或无细胞的表达系统中发生,之后病毒结构可以被组装和重建。 VLP凭借其卓越的免疫原性,在预防医学...
5.3 Virus-like particle (VLP) vaccines A virus-like particle (VLP) vaccine produced by the co-expression of the P1 region (VP4, VP2, VP3, and VP1) and viral protease 3CD with recombinant baculovirus was examined for its ability to produce immune responses and protection against lethal chall...
This, coupled with their size and repetitive structure, makes VLPs ideal vaccine candidates compared to subunit and DNA vaccines. As VLPs are empty shells, they can be less stable than the native virus in cases where the viral nucleic acid contributes to particle stability. This can cause ...
vaccinesrecombinantvirusparticle疫苗case CaseStudy:Recombinantvirus-likeparticlevaccines:Recombivax-HB®andGardasil®Sept22,2009VaccineBasicResearch,MerckResearchLaboratoriesVLPsasimmunogens•Commonlymoreimmunogenicthansubunits•Stimulatebothhumoralandcellulararmsoftheimmunesystem•Spatialstructureofdisplayenhanceproduct...
Paramyxovirus structural proteins within a virus-like particle (VLP) comprise one example of such a vaccine. 病毒样颗粒(VLP)内的副粘病毒结构蛋白包含这种疫苗的一个实例。 ip.com 2. The Structure and Virus-like Particle Vaccine of the HIV-1 Capsid Protein HIV-1壳体蛋白的结构及其病毒样颗粒疫苗 ...
in the placebo group. durability of the immune response was demonstrated through 72 weeks after vaccination. conclusions and relevance among healthy adults in a chikungunya endemic population, a virus-like particle vaccine compared with placebo demonstrated safety and tolerability. phase 3 trials are ...
例句 释义: 全部,病毒样颗粒,类病毒微粒 更多例句筛选 1. Paramyxovirus structural proteins within a virus-like particle (VLP) comprise one example of such a vaccine. 病毒样颗粒(VLP)内的副粘病毒结构蛋白包含这种疫苗的一个实例。 ip.com© 2024 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
2) virus-like particulate peptide-nucleotide vaccine 病毒样颗粒肽-核酸疫苗3) Virus-like particle 病毒样颗粒 1. Expression, purification and immunogenicity of a novel hepatitis E virus-like particle; 一种新型戊型肝炎病毒样颗粒的表达、纯化及其免疫原性 2. Expression,purification and immunogenicity ...