Results Chimeric viruses recapitulate the structure of wild-type virions. To confirm the structural mimicry of the chimeric viruses at the atomic level we determined the cryo-EM reconstructions of wild- type WNVKUN (Kunjin strain—KUN), which can be handled in BSL2 equivalent cryo-EM facilities...
Results Chimeric viruses recapitulate the structure of wild-type virions. To confirm the structural mimicry of the chimeric viruses at the atomic level we determined the cryo-EM reconstructions of wild- type WNVKUN (Kunjin strain—KUN), which can be handled in BSL2 equivalent cryo-EM facilities...
It has been shown that sGP is produced in larger quantity than GP during replication and may therefore act as a decoy by binding to neutralizing antibodies13. Such com- plexity in GP structure and insidious tactics to evade and distract immune recognition may partially explain why majority of ...
As used herein, a “flexible linker” is a linker which does not have a fixed structure (secondary or tertiary structure) in solution and is therefore free to adopt a variety of conformations. Generally, a flexible linker has a plurality of freely rotating bonds along its backbone. In ...
The DNA and amino acid sequence information provided by the present invention also makes possible the systematic analysis of the structure and function of the viral genes and their encoded gene products. Knowledge of a polynucleotide encoding a viral gene product of the invention also makes available...
Cultured tomatoes are often exposed to a combination of extreme heat and infection with Tomato yellow leaf curl virus (TYLCV). This stress combination leads to intense disease symptoms and yield losses. The response of TYLCV-susceptible and resistant tom
The results overall are consistent with the idea that GW5074 binds to the ARM repeat domain of IMPα to alter structure/conformation, which would appear to be the basis of inhibited binding to IMPβ1. Cells 2019, 8, 281 CCeelllsls 2 2001199, ,8 8, ,x x 9 of...
Furthermore, this study can be used as a geospatial guide to identify areas of high disease transmission risk and to inform national public health surveillance programs. Keywords: Nipah virus; ENMeval; BIOMOD2; risk mapping; ecological niche modeling; disease biogeography; infectious disease ...