Furthermore, administration of DEF201 at 6 h and 12 h post-lethal EV71 infection of mice resulted in full and partial protection, respectively [241]. Viewed together, these in vivo studies provide a rationale for the evaluation of the prophylactic and therapeutic effects of adenovirus-...
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Influenza A activity21,26, these results indicate that Ci extract displays broad-spectrum antiviral activity against multiple unrelated, major human viral pathogens (i.e. HIV, Marburg virus, Ebola virus, Influenza A virus). Different experimental assays designed to investigate the mode of antiviral a...
This may result in a decrease in protection against a new field strain provided by a vaccine strain. Therefore, the OIE expert panel on EIV vaccines annually reviews antigenic differences in field strains and, based on this, advises on vaccine strain composition. EIV strains of the Florida ...
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EBOTAb has been shown to confer protection at levels of 83.3%, 50% and 33.3% when treatment was first started on days 3, 4 and 5 post-challenge, respectively. These timepoints of when EBOTAb treatment was initiated correspond to when levels of EBOV are detectable in the circulation and ...
Hepatitis B (HepB) vaccines are composed of HBsAg adsorbed to an adjuvant ofaluminum hydroxideor aluminum hydroxyphosphate sulfate.148,149HBsAg elicits development of the neutralizing antibody, anti-HBs, which confers protection from infection. Plasma-derived vaccines were manufactured from HBsAg purified...