In addition to the interest in viruses that arises from their medical and scientific importance, viruses form a fascinating evolutionary system. There is debate as to how ancient are viruses. Some argue that RNA viruses contain remnants of the RNA world that existed before the invention of DNA....
Sign in to download full-size image Figure 6.1.Chemical structure of DANA with neuraminidase inhibitors. As compared to a transition state analogue of sialic acid, DANA (2,3-dehydro-2-deoxy-N-acetylneuraminic acid), oseltamivir has a hydrophobic pentoxil ether side group, the C6-carbon of th...
New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccin
Mississippi State Health Officer Dr. Thomas Dobbs, right, listens as Gov. Tate Reeves responds to a reporter's question regarding his executive order mandating that all adults and students wear masks in schools, unless there's a medical reason that prevents them from doing so, durin...
Full size image In addition, we quantified the IgG fraction targeting DIII. DIII is often used for serological diagnosis35 and although cross-reactive epitopes have been described36,37, responses to DIII are generally virus-specific38. As observed for anti-sE IgG antibodies, TBEV-pre-vaccinated...
FGS, HPV and CC are suspected to be highly prevalent in the country though little is known about the medical needs associated with these diseases. Consequently, this hampers the adaptation of guidelines and health services for prevention, control and management [43]. This study is based on data...
Mpox virus (MPXV) primarily infects human skin to cause lesions. Currently, robust models that recapitulate skin infection by MPXV are lacking. Here we demonstrate that human induced pluripotent stem cell-derived skin organoids are susceptible to MPXV in
Because we measured DAA treatment in terms of filled prescriptions, we did not include prescriptions written but not filled. Patients may also have received DAA treatment outside of the VHA. In addition, factors such as estimated life expectancy, which could be associated with DAA prescribing, ...
Prevention of hMPV infection remains the most desirable form of intervention, but no studies on hMPV vaccine products for humans have been reported.16 Read full chapterView PDFExplore book Viral Respiratory Infections Michael J. Tan, in Netter’s Infectious Diseases, 2012 Human Metapneumovirus ...
The next highest potential exposure sites, in order, were medical facilities, “work,” grocery stores, casinos, schools and long-term care facilities. After that, air travel, general stores or shops, gas stations, group living, gyms, bars, convenient stores and “other places with l...