This diagram gives some examples. A. Linear single-stranded DNA molecule of the kind found in parvoviruses. B. Linear double-stranded DNA molecule occurring in herpes virions and adenovirions. C. Single-stranded circular DNA which is found in the bacteriophage ØX174. D. Covalently closed ...
and this priming was sufficient to elicit a level of anti-H9 HA antibody response that was associated with protection after a single dose of the H9N2 vaccine. However, in persons younger than 32 years, who were essentially unprimed, even two doses of vaccine was suboptimal, because a s...
Current literature has suggested that RAB11 is exploited by enteroviruses for modulating the cholesterol level in replication organelles (RO) to create a microenvironment favourable for viral RNA synthesis [25]. Such cholesterol re-routing is associated to PI4KB, which is recruited to the ROs by ...
Humoral Immune Response in mRNA-A-LNP and mRNA-B-LNP-Vaccinated Mice. Female BALB/c mice were immunized with 40 μg mRNA-A-LNP vaccine or 40 μg mRNA-B-LNP vaccine or were designated negative controls (n = 10). Two intramuscular immunizations were on day 0 and day 14, resp...
We thank Laura Bollinger (NIH/NIAID Integrated Research Facility at Fort Detrick, Frederick, MD, USA) for critically editing the manuscript and William Discher (USAMRIID, Fort Detrick, Frederick, MD, USA) for the diagram used in Fig. 4. This work was supported in part through the prime contr...
Schematic diagram showing the viral particle structure of SARS-CoV-2(A), and the genome organization of SARS-CoV-2 genes(B). The structural components of the spike (S) protein; S2 contains signal peptide (SP), N-terminal domain (NTD), and receptor binding domain (RBD). The S1 contains...
(a) Linear diagram of GP indicating sequence features. The cellular Golgi endopeptidase furin cleaves the precursor subunit GP0 to GP1 and GP2. sp, signal peptide. b, GP1 ‘base’ subdomain. h, GP1 ‘head’ subdomain. RBS, putative receptor-binding sequence. FL, GP2 fusion loop. HR1, ...
SCHEME 1. Diagram of isolation of reconstitute TMV. It would be interesting to know whether under standard conditions TMV proteins recognize TMV RNA, because TMV reconstitution might prove a useful system in studying the general problem of specific RNA-protein interactions; indeed, this type of inte...
(solid rectangles), which contain the DNA cleavage/packaging signals, are located at the junction between the long and short segments and at both termini. FIG. 1B is a schematic diagram of the HSV-1 clones from cosmid set C6Δa48Δa (cos6Δa, 28, 14, 56, 48Δa). The deleted a ...
FIG. 1 presents a diagram of Bifidobacteriaceae family. FIG. 2 presents results of ELISA of HBsAg using a reagent for diagnosing hepatitis A and B (Enzygnost HBsAg monoclonal, Behring, Germany). FIG. 3 presents results of ELISA of HBsAg for the separated 6 kinds oflactobacillususing a reagen...