Emerging viral infections are becoming a serious problem in Europe in the recent years. This is particularly true for severe acute respiratory syndrome (SARS), West Nile virus (WNV) disease, Toscana virus (TOSV) disease, and potentially for avian influenza virus (H5N1). In contrast, emergence ...
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) hospitalizations and deaths disportionally affect males and older ages. Here we investigated the impact of male sex and age comparing sex-matched or age-matched ferrets infected with SARS-CoV-2. Differences in temperature regulation was ...
Viral myocarditis is characterized by infiltration of mononuclear cells essential for virus elimination. GPR15 has been identified as a homing receptor for regulatory T cells in inflammatory intestine diseases, but its role in inflammatory heart diseases
SARS-CoV, severe acute respiratory syndrome coronavirus; MERS-CoV, Middle East respiratory syndrome coronavirus; RdRp, RNA-dependent RNA polymerase; crRNA, CRISPR RNA; DAPI, 4′,6-diamidino-2-phenylindole; qRT-PCR, quantitative reverse transcription PCR; SEM, standard error of the mean. mRNA-...
Secondary events were hepatic events, defined based on ICD-9-CM codes of ascites, spontaneous bacterial peritonitis, variceal bleeding, hepatorenal syndrome, hepatic encephalopathy, liver transplantation, and/or liver-related mortality (Table S1). Liver cirrhosis was identified using ICD-9-CM diagnosis...
Adachi A, Gendelman HE, Koenig S, Folks T, Willey R, Rabson A, Martin MA: Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol. 1986, 59 (2): 284-291. PubMed Central CAS PubMed Google Schol...
Intralesional injection of small amounts of a 0.1% solution of bleomycin in saline often cures stubborn plantar and periungual warts. However, Raynaud syndrome or vascular damage may develop in injected digits, especially when the solution is injected at the base of the digit, so caution is war...
Learn about the veterinary topic of Astrovirus Infections in Poultry. Find specific details on this topic and related topics from the Merck Vet Manual.
Approximately 30 MDA5 point mutations have been linked to severe autoinflammatory disorders in heterozygous human patients, including Aicardi–Goutières syndrome (AGS), Singleton–Merten syndrome (SMS), spastic-dystonic syndrome, and neuroregression25,26,27. Pathogenic MDA5 mutations are associated with ...
A large-scale survey of the novel 15q24 microdeletion syndrome in autism spectrum disorders identifies an atypical deletion that narrows the critical region. Mol Autism. Mar. 19, 2010;1(1):5. doi: 10.1186/2040-2392-1-5. McManus, et al. Gene silencing in mammals by small interfering ...