Recently, two groups of rhodopsin genes were identified in large double-stranded DNA viruses. The structure and function of viral rhodopsins are unknown. We present functional characterization and high-resolution structure of an Organic Lake Phycodnavirus rhodopsin II (OLPVRII) of group 2. It form...
Understanding the Structure and Function of Viral Glycosylation by Molecular Simulations: State-of-the-Art and Recent Case StudiesThe chemical nature and heterogeneity of most complex carbohydrates makes their structural characterization very difficult, if not impossible, through experimental structural biology...
This 120-base RNA has many novel and distinctive features. It contains strong secondary structure, is tightly folded, and unusually stable. Upon interaction with ion and proteins, it has a knack to adapt numerous conformations to perform versatile function. It can be easily manipulated to form ...
This review examines pRNA as a noncoding RNA of novel structure and function. In order to highlight the reasons for exploring the structure and function of pRNA, we (1) provide an overview of Φ29-like bacteriophage and the Φ29 DNA packaging motor, including putative motor mechanisms and ...
MxB manipulations disrupt mitochondrial structure and function Based on the morphological observations described above, we next test whether manipulation of MxB levels might alter mitochondrial morphology. Hep3B cells transfected with either GFP-tagged or untagged wild-type (WT) or GTPase-defective mutant...
Chapter three of this thesis describes the solution structure of the ... AW Jacobitz 被引量: 0发表: 2015年 A Biochemical Investigation of Saccharomyces cerevisiae Trm10 and Implications of 1-methylguanosine for tRNA Structure and Function. This dissertation focuses on the biochemical characterization ...
To test the functional significance of this predicted structure, we developed a flow-cytometry-based assay that measures cytosolic exchange across the conjugation junction to rapidly probe the effects of HAP2 mutations in the Tetrahymena system. Using this assay, alterations to a region in and ...
Our results support the view that reorganization of the Golgi complex during myogenesis involves at least a partial loss of both Golgi structure and function. 展开 关键词: LECTIN IMMUNOGLOBULIN GLYCOCONJUGATES HISTOCHEMISTRY AFFINITY CHROMATOGRAPHY TESTES SPERMATOZOA DOI: 10.1006/excr.1995.1296 被引量: 8...
Blondot, M.-L. et al. Structure and Functional Analysis of the RNA- and Viral Phosphoprotein-Binding Domain of Respiratory Syncytial Virus M2-1 Protein.PLoS Pathog.8, e1002734 (2012). ArticleCASGoogle Scholar Tran, T.-L. et al. The Respiratory Syncytial Virus M2-1 Protein Forms Tetramer...
Plant genotype is recognized to contribute to variations in microbial community structure in the rhizosphere, soil adherent to roots. However, the extent to which the viral community varies has remained poorly understood and has the potential to contribu