*使用本品系发表的文献需注明: Vip-IRES-Cre mice (Cat. NO. NM-KI-200100) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 图1 VipCre/+; Rosa26tdTomato/+小鼠脑部tdTomato的表达情况。 VipCre/+; Rosa26tdTomato/+双转基因鼠,可在小鼠大脑皮层中检测到tdTomato的表达。
1a2). Third, VIP-IRES-Cre mice were mated with Ai14 mice so that VIP-ACs expressed tdTomato and exhibited red fluorescence (Fig. 1a3). We found that the cell bodies of VIP-ACs were filled with red fluorescence in VIP::Ai14 mice, whereas yellow‒green fluorescence was observed only ...
1c, d), which we could also observe in densely tdTomato-labelled cortex of VIP-IRES-Cre mice crossbred with the Ai14 reporter line53 (Supplementary Fig. 1). We continued our experiments using the AAV-approach, which provided a sparse expression pattern that was limited to a subset of ...
In all, 2–5-month-old male and female VIP-IRES-cre mice (Jackson Laboratory, stock no. 010908) were used in this study. Male mice were used for electrophysiology, VSD and calcium imaging experiments, as well as the first cohort of behavioral studies testing the chemogenetic therapy (see ...
(Fig.1c, d), which we could also observe in densely tdTomato-labelled cortex of VIP-IRES-Cre mice crossbred with the Ai14 reporter line53(Supplementary Fig.1). We continued our experiments using the AAV-approach, which provided a sparse expression pattern that was limited to a subset of ...
Mice Mice used in this work include VIP-IRES-Cre (Jackson Laboratory Stock, JAX, 010908), crossed to C57BL/6N (Charles River, C57BL/6NCrl), VIP-IRES-Cre crossed to Ai162 (GCaMP6s reporter line, JAX, 031562), and VIP-IRES-Cre crossed to Ai140 (GFP reporter line, JAX, 30220). Fo...
*使用本品系发表的文献需注明: Vip-KO(2) mice (Cat. NO. NM-KO-210298) were purchased from Shanghai Model Organisms Center, Inc.. 疾病预测 原发性肺动脉高压 Primary Pulmonary Hypertension 近似模型的表型 MGI:3054170 参考文献 Said SI, Hamidi SA, Dickman KG, Szema AM, Lyubsky S, Lin RZ,...
mCherry-WPREs virus into the SCN of VIP-IRES-Cre (VIP-hM4D(Gi)-mcherry) mice (Fig.2b). To exclude the effects of virus injection, we repeated the pharmacological experiments on VIP-hM4D(Gi)-mcherry mice (Fig.2e). We found that VIP-hM4D(Gi)-mcherry mice in the DexM group ...
rodentium-infected VipIRES-creor VipIRES-crehM3Dqfl-stop-fl/+ mice treated with CNO (1 mg kg−1, daily, 1–4 days post-infection (yellow rectangle)). Vehicle, n = 11 mice; CNO, n = 9 mice. e, f, Infectious burden in faeces of VipIRES-crehM3Dqfl-stop-fl/+ mice (...
Electrophysiological experiments were performed on male and female mice (age 41–164 days), that were heterozygous for VIP-IRES-Cre and either Ai32 (VIP+/cre; Ai32+/−, termed VIP-ChR2; experiments presented in Figs. 1–4 and Supplementary Figs. 1–7) or Ai40 (VIP+/cre; Ai40+/...