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In cells infected with wild-type virus, Vif binds to APOBEC3G preventing its encapsidation. HIV-1 Vif does not bind tightly with mouse or simian APOBEC3G, and thus fails to prevent their encapsidation. Some features of the model are supported by the data but not fully established. Efficient ...
...Marketing_Spend",data=sdata).fit() print(1/(1-model.rsquared)) 执行结果 2.026140603233619 上面我仅仅计算了以RD_Spend为因变量计算的VIF 1.7K30 如何消除多重共线性 本文将向您展示如何使用Python消除多重共线性。 数据源 为了演示,我们将使用一个名为Rain in Australia的数据集。它描述了不同日期和...
could co-fold well with vif when they were coexpressed with elob-eloc, supporting our data. over-expression of elob mutant with a 34-residue deletion in the cooh-terminal tail blocks vif-induced a3g degradation several lines of evidence have indicated that the vif-binding motif is located ...
2023, Science Advances Recent advances in poor HIV immune reconstitution: what will the future look like? 2023, Frontiers in MicrobiologyPresent address for Seung Joong Kim: Department of Physics and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon...
Other data are available from corresponding authors upon reasonable request. References Lecossier, D., Bouchonnet, F., Clavel, F. & Hance, A. J. Hypermutation of HIV-1 DNA in the absence of the Vif protein. Science 300, 1112 (2003). Article CAS PubMed Google Scholar Mangeat, B. ...
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Data availability The model of the PPP2R5A–VCBC complex has been deposited in the Protein Data Bank (PDB) with accession code PDB8SZK. The cryo-EM map of the PPP2R5A–VCBC complex has been deposited in the Electron Microscopy Data Bank (EMDB) with accession code EMD-40919. The struc...
The genetic distance was 1.8 times higher in the sequences harboring SC than in the sequences without SC (p<0.001). Q135P in thevifgene is significantly associated with rapid progression to AIDS (p<0.01).#Our data show that KRG might induce s螖 in the vif-vprgenes and that vif-vpr...
The infectivity of each virus produced in the absence of APOBEC3G was normalized to 100%. APOBEC3G and Vif were detected by Western blot of lysates from virus-producing cells. Data are representative of three independent experiments. B, 293T cells were transfected with pNLA1.Vif-FLAG (10 μ...