然后使用新公式运行旧的lm函数 model <- lm(y ~ x1 + x3 + ... + x100) 我已经学习了如何检索具有最高VIF系数的解释变量的名称: max_vif <- function(x) { nameofmax <- rownames(which(vifac== max(vifac), arr.ind = TRUE) 浏览45提问于2020-04-30得票数 3 1回答
The R function vif() [car package] can be used to detect multicollinearity in a regression model: car::vif(model1) ## crim zn indus chas nox rm age dis rad ## 1.87 2.36 3.90 1.06 4.47 2.01 3.02 3.96 7.80 ## tax ptratio black lstat ## 9.16 1.91 1.31 2.97 In our exampl...
We further tested the Vif mutants that affected the PPP2R5A interaction for their ability to induce A3G degradation in cells to compare the binding requirements and to verify that the lack of PPP2R5A degradation was not due to structural alterations resulting in loss of all Vif function (Fig...
The best-characterized function of HIV-1 Vif is counteraction of the APOBEC3 (A3) DNA cytosine deaminases [1]. In the absence of Vif, A3s package into nascent HIV-1 particles and generate C-to-U lesions in the viral cDNA, causing genomic strand G-to-A hypermutation and inhibiting revers...
In contrast to CXCR4 KO, which affects initial infection, the primary CD4+ T cell results for ARIH2 point to a function in later stages of the HIV life cycle, either by reducing the formation of newly formed virus particles or by decreasing their infection rate. Taken together, the results...
The timing model provided in Figure 18 shows the specific delay paths. Once the implementation of a given function is determined either conceptually or from the software report file, the delay path of the function can easily be determined from the timing model. The Lattice design tools ...
However, HIV-1 evolution and quasi-species diversification within a single human being might lead to the accumulation of mutations in the Vif region, which might affect protein function and have clinical significance by either decreasing viral replication or affecting integration and transmission. The ...
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