lipo-viro-particlelipoprotein lipaseviral loadObjective Circulating hepatitis C virus (HCV) virions are associated with triglyceride-rich lipoproteins, including very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), designated as lipo-viro-particles (LVPs). Previous studies showed that ...
Low density lipoprotein (LDL) is the predominant atherogenic lipoprotein particle in the circulation. Conventionally, a fasting lipid profile has been used for atherosclerotic cardiovascular disease (ASCVD) risk assessment. A non-fasting sample is now regarded as a suitable alternative to a fasting samp...
The concentration of lipoprotein(a) (Lp(a)) tends to be elevated. Finally, the HDL particle changes its composition during inflammation into paradoxically pro-atherogenic acute-phase HDL. Table 1. The spectrum of lipid changes and lipoprotein abnormalities in early and advanced stages of chronic ...
Aim: Diabetic dyslipidaemia, characterized by hypertriglyceridaemia as a result of elevated serum very-low-density lipoprotein (VLDL) concentrations, contributes to the increased risk of cardiovascular disease (CVD) in type 2 diabetes (T2DM). Proprotein convertase subtilisin/kexin type 9 (PCSK9) may...
particle within the liver and of cholesterol provided by CETP. Hence, the cholesterol content of VLDL increases after VLDL secretion. In contrast, the TG and PL content of the secreted VLDL decreases due to progressive degradation of TG and PL by lipoprotein lipase (LPL) and endothelial lipase ...
Cell surface assembly of lipoprotein(a) in primary cultures of baboon hepatocytes. Lipoprotein(a) (Lp(a)) consists of a low density lipoprotein particle in which apolipoprotein(a) (apo(a)), is disulfide linked to apoB. Lp(a) is produced b... AL White,RE Lanford - 《Journal of ...
High carbohydrate (CHO) diets cause accumulation in plasma of larger, triglyceride (TG)-enriched very low density lipoprotein (VLDL) particles. In man, the composition of the VLDL is changed by such diets as well. The source of the altered VLDL particles is presumed to be the liver, but th...
Hsiang-Chun Lee Wei-Chung Cheng Yi-Hsiung Lin Scientific Reports (2023) The role of postprandial very-low-density lipoprotein in the development of atrial remodeling in metabolic syndrome Hsiang-Chun Lee Shyi-Jang Shin Yi-Hsiung Lin Lipids in Health and Disease (2020)Download...
The turnover and the catabolic fate of the B apoprotein of very low density lipoprotein (VLDL-B) was studied in 15 normal and hyperlipidemic subjects using reinjected autologous VLDL labeled with radioiodine. The specific radioactivity-time curve of the B apoprotein in total VLDL (S(f)20-400)...
In dysbetalipoproteinemic plasma, the metabolic precursors of the largest product were shifted from the IDL to the small VLDL (beta-VLDL) particle distribution. Since beta-VLDL are known to predispose to accelerated atherosclerosis in dysbetalipoproteinemia, it may be that metabolically homologous ...