Balduzzi A, Conter V, Uderzo C, Valsecchi MG. Transplantation in childhood very high risk acute lymphoblastic leukemia in first complete remission: where are we now? J Clin Oncol 2007; 25: 2625-2626; author reply 2627-8.Balduzzi A, Conter V, Uderzo C, Valsecchi MG. Transplantation in ...
In multivariate analysis, donor-type appears as a negative risk-factor for OS, EFS, and NRM. This paper demonstrates the impact of donor type on overall results of allogeneic stem cell transplantation for very-high risk pediatric acute lymphoblastic leukemia with worse results when using MMD stem...
Toxicity, Lymphoblastic Leukemia, Acute, Childhood, ClofarabineBackgroundChildren, adolescents and young adults with very high-risk (VHR) B acute lymphoblastic leukemia (B-ALL) have a poor outcome and novel therapies are needed for this subgroup. AALL1131 evaluated post-Induction therapy for patients...
Doug Smith, MD, provides context for the AALL1131: a phase III randomized trial for newly diagnosed high risk b-precursor acute lymphoblastic leukemia (ALL). Video Player is loading. This is a modal window. This video is either unavailable or not supported in this browser Error Code: MED...
Full haplotype-mismatched hematopoietic stem-cell transplantation: a phase II study in patients with acute leukemia at high risk of relapse. PURPOSE: Establishment of hematopoietic stem-cell (HSC) transplantation from mismatched relatives is feasible for patients with acute leukemia. As our orig... ...
Endothelial-derived small extracellular vesicles support B-cell acute lymphoblastic leukemia development ArticleOpen access26 September 2023 Endothelial cell-specific expression of serine/threonine kinase 11 modulates dendritic cell differentiation Article
86 High-risk acute lymphoblastic leukemia (ALL) has been proposed to arise from a limited immature leukemia-initiating cell (LIC) compartment that may confer treatment resistance. Recent reports challenge this view. Using syngeneic leukemia mouse models, higher frequencies of LIC were detected. More...
Childhood Acute Lymphoblastic Leukemia: How to Cure the Very High Risk?ALLacute lymphoblastic leukemiachildhooddoi:10.1016/j.clml.2019.07.396Ching-Hon PuiClinical Lymphoma, Myeloma & Leukemia
acutelymphoblasticleukemiacompleteremissionhematopoieticstemcelltransplantationSchechter T, Ishaqi KM, Rojas M, Irina Z, Doyle JJ, Gassas A. Outcome of hematopoietic stem cell transplantation of children with very high risk acute lymphoblastic leukemia in first complete remission. Pediatr Transplantation 2010...
Leukemia & LymphomaCarella AM, Pollicardo N, Carlier P, et al. (1992) “Normal” peripheral blood stem cells (PBSC) mobilization by myelosuppressive chemotherapy in very high risk acute lymphoblastic leukemia (ALL) with cytogenetic translocations. Leukemia and Lym-phoma 7 [Suppl 2]: 19–21...