Insynastry, the Vertex is considered almost like a part of thePrimal Triad(Sun, Moon, Ascendant), and you can see connections with people who have a natal planetconjunctyour Vertex or Anti-Vertex. In thecomposite chart, the Vertex can be strong with those you have a fated connection with,...
Cafe Astrology explores the meaning of the Vertex in astrology. It's most used in synastry, but is also considered a wish point of destiny in the natal chart.