Cardiac troponin (cTn) assays have evolved through several decades to the most recent generation coined ‘high sensitivity’ (hsTn) assays. In order to be assigned as ‘high sensitivity’, the required attributes are an imprecision of ≤10 % CV (coefficient of variation) at the 99th percent...
This study aimed to investigate the potential of autophagy-related genes (ATGs) as a prognostic signature for HCC and explore their relationships with immune cells and immune checkpoint molecules. A total of 483 samples were collected from the GEO databa
A gene expression profile of OS in public databases was examined to identify differentially expressed BMP-related genes (DEBRGs). Further pathway enrichment analysis was conducted, and the related network of protein–protein interactions (PPIs) was built. Subsequently, combining univariate, multivariate ...
The “Rhubarb-Peach kernel” herb pair (RP) is a core medical pair of classical disperse stasis formula and consists of two TCM drugs: Rheum palmatum L., Rhizome and root (R, dahuang), and Prunus persica (L.) Batsch, seed (P, taoren). In traditional Chinese medicine, RP has been ...
Under a Creative Commons license open accessAbstract Objective To evaluate accuracy of an innovative “Skywalker” system, a newly designed, robot-assisted operation system for orthopaedics via a clinical trial at knee joint. Methods We conducted a prospective analysis of the clinical data of 31 pat...
Artemisia argyi is a traditional herbal medicine belonging to the genus Artemisia that plays an important role in suppressing inflammation. However, the chemical constituents and underlying mechanisms of its therapeutic potential in neuroinflammation are
Luteolin is an active ingredient in various traditional Chinese medicines for the treatment of multiple tumors. However, the mechanisms of its inhibitory effect on osteosarcoma proliferation and metastasis remain unclear. To elucidate the anti-osteosarco
A Western blot was performed to detect the expression of IL-1B and IL-6 in ASP-treated KGN cells. β-actin was used as a normalization standard. B The effects of ASP on inflammatory factors in LPS treated KGN cells were determined by Western blot analysis. β-actin was used as a ...
activation of Caspase-1 to further cleave Caspase-1 into cleaved Caspase-1, which cleaves GSDMD to cleave GSDMD.44Cleavage of GSDMD further promotes cell pyroptosis, and this process results in the production of large amounts of IL-1β and IL-18, ultimately leading to DNA damage.44When ...
Glioma is the most common cancer in the central nervous system, and low grade gliomas are notorious for many types of tumors and heterogeneity. PROS1 not only plays an important role in the blood coagulation system, and recent studies have found that it