expression is due to the widespread occurrence of EMT in diffuse-type GC when compared to intestinal-type GC18. Gao et al. found that miR-145 was significantly down-regulated in GC and metastatic tumor tissue. Results of functional experiments suggest that miR-145 can inhibit the migration, in...
Clear cell renal cell carcinoma (ccRCC) is a malignant tumor of the urinary system. To explore the potential mechanisms of DHODH in ccRCC, we analyzed its molecular characteristics using public databases. TCGA pan-cancer dataset was used to analyze DHODH
Nomilin is a limonoid compound known for its multiple biological activities, but its role in triple negative breast cancer (TNBC) remains unclear. This study aims to uncover the potential therapeutic effect of nomilin on TNBC and elucidate the specific m
Cold stimulation reduces the quality of animal products and increases animal mortality, causing huge losses to the livestock industry in cold regions. Long non-coding RNAs (lncRNAs) take part in many biological processes through transcriptional regulatio
This results in the induction of apoptosis and suppression of CRPC cell proliferation [8,9]. Many studies demonstrate the positive effects of enzalutamide in CRPC patients, such as significantly prolonging survival after chemotherapy [10]. However, insensitivity to enzalutamide is found in almost ...
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Figure 2. Exploration of Stroma- and Metastasis-Associated Genes. (A–C) Simulation of the effect of different matrix stiffness on the expression of key genes in EMT In vitro; (D) Volcano plot of stroma-associated DEGs based on TCGA-PAAD data; (E) Volcano plot of metastasis-associated DEG...
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sensors Article Verification of a Method for Measuring Parkinson's Disease Related Temporal Irregularity in Spiral Drawings Somayeh Aghanavesi 1,* ID , Mevludin Memedi 2, Mark Dougherty 1, Dag Nyholm 3 and Jerker Westin 1 1 School of Technology and Business Studies, Computer Engineering, Dalarna...