Ventromedial prefrontal cortex (vmPFC) is vital for decision-making. Functional neuroimaging links vmPFC to processing rewards and effort, while parallel work suggests vmPFC involvement in prosocial behaviour. However, the necessity of vmPFC for these functions is unknown. Patients with rare focal vmPFC...
Ventromedial prefrontal cortex (VMPFC) The VMPFC consists primarily of the orbitofrontal cortex and the anterior cingulate, and is also known as the ‘limbic’ cortex (seeFig. Ib). It has been demonstrated that the VMPFC plays a key role in decision making,social cognitionand social judgementd....
Patients with major depressive disorder (MDD) often have structural and functional deficits in the ventromedial prefrontal cortex (vmPFC), but the underlying molecular pathways are incompletely understood. The neuropeptide precursor VGF (non-acronymic) plays a critical role in depression and antidepressant...
The ventromedial prefrontal cortex (vmPFC) is considered critical for decision-making. Functional neuroimaging studies indicate that vmPFC is key for processing costs such as effort and benefits such as rewards, as well as integrating these to compute value1,2,3,4,5,6,7,8. Activity in vmPFC h...
Fig. 5. Timecourse of value-related effects in the ventromedial prefrontal cortex (vmPFC) over the course of a trial in the three conditions. Left column: effects of value difference and value sum on BOLD activity in vmPFC. Right column: Effects of chosen and unchosen option value on vmPFC...
Animal and human neuropsychological work has demonstrated that lesions in the orbital and medial prefrontal cortex (PFC) are associated with impairments in reversal learning.20-23 Human neuroimaging work in healthy adults has also implicated the ventromedial PFC (vmPFC) as well as the ventrolateral (...
The region of the brain thought to be a neuroanatomic correlate of these behaviors, the ventromedial prefrontal cortex (vmPFC) was structurally abnormal in the boys with ICLP. Compared to healthy boys, the vmPFC was propor- tionately enlarged. This is despite the finding in our previous work ...
C, Mean activitation time course for the significant ventromedial prefrontal cortex (vmPFC) region (blue cluster from peak period) identified during the 0.5-μg infusion. Shaded lines indicate SEMs. BOLD indicates blood oxygenation level–dependent response; GAD, generalized anxiety disorder; and HC...
(4 patients with bilateral hippocampal damage and severe declarative memory impairment, 4 patients with ventromedial prefrontal cortex [vmPFC] damage, and ... J Kurczek,S Brown-Schmidt,M Duff - 《Journal of Experimental Psychology General》 被引量: 46发表: 2013年 The Neuro-Computational Architectur...
Prefrontal cortex (PFC) is sensitive to the complexity of incoming information1 and theoretical perspectives suggest that a core function of PFC is to focus representation on goal-relevant features by filtering out irrelevant content2,3. In particular, ventromedial PFC (vmPFC) is thought to represent...