The ventromedial prefrontal cortex (vmPFC) is considered critical for decision-making. Functional neuroimaging studies indicate that vmPFC is key for processing costs such as effort and benefits such as rewards, as well as integrating these to compute value1,2,3,4,5,6,7,8. Activity in vmPFC h...
在生物学与医学领域,“ventromedial”主要用来描述与生物体内部某些特定结构或功能区域相关的位置关系。例如,在大脑结构中,“ventromedial prefrontal cortex”(VMPFC),即正中前额叶皮层,是一个关键区域,与个体的安全感、行为能力丧失的感受、对待损失的态度、决策制定以及自我模型的产生等密切相关。...
This revealed an activation pattern consistent with a relative functional double dissociation between the temporoparietal junction (TPJ) and ventro-medial prefrontal cortex (vmPFC). Difficult moral decisions activated bilateral TPJ and deactivated the vmPFC and OFC. In contrast, easy moral decisions ...
Prefrontal cortex (PFC) is sensitive to the complexity of incoming information1and theoretical perspectives suggest that a core function of PFC is to focus representation on goal-relevant features by filtering out irrelevant content2,3. In particular, ventromedial PFC (vmPFC) is thought to represents...
Prefrontal cortex Theventromedial prefrontal cortex(vmPFC), encompassing the rostral anterior cingulate cortex, medial prefrontal cortex, subgenual cingulate cortex, and orbitofrontal cortex, has been shown to play a key role in the extinction of conditioned fear responses, and importantly, in the mainten...
Using functional magnetic resonance imaging during an autobiographical memory recall task, we found that the blood oxygen level dependent (BOLD) signal in ventromedial prefrontal cortex (vmPFC) was parametrically modulated by the affective values of items in participants' memories when they were recalling...
The ventromedial prefrontal cortex (vmPFC) is associated with emotional states that can be characterized as positive affect. Moreover, a variety of psychiatric disorders that are associated with disturbed reactions toward reward- or safety-signaling stimuli reveal functional or structural anomalies within ...
This revealed an activation pattern consistent with a relative functional double dissociation between the temporoparietal junction (TPJ) and ventro-medial prefrontal cortex (vmPFC). Difficult moral decisions activated bilateral TPJ and deactivated the vmPFC and OFC. In contrast, easy moral decisions ...
The ventral striatum and ventromedial prefrontal cortex (vmPFC) are two central nodes of the "reward circuit" of the brain. Human neuroimaging studies have demonstrated coincident activation and functional connectivity between these brain regions, and animal studies have demonstrated that the vmPFC modulat...