VEGF PathwayComplexity ValueKEGG DatabaseModularizationNewman’s Community Finding AlgorithmKernighan-Lin’s AlgorithmFarhat’s Algorithmand Greedy AlgorithmIn biology, signal transduction refers to a process by which a cell converts one kind of signal or stimulus into another. It involves ordered ...
2.蛋白质-蛋白质相互作用(protein-protein interaction,PPI)网络:将交叉靶点信息导入String数据库,以置信水平>0.4为筛选条件下载交叉靶点的PPI信息,并使用Cytoscape软件进行可视化。 3.基因本体(gene ontology,GO)功能与京都基因与基因组...
3c). Kyoto Encyclopedia of genes and genomes (KEGG) is a comprehensive database that combines information on genomic, chemical, and system functions. KEGG analysis showed that the differentially significantly enriched pathways included tryptophan metabolism, Wnt signaling pathway, and VEGF signaling ...
Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis further revealed that the DEGs were implicated in the regulation of neuroactive ligand–receptor interaction; NF-kappa B, TNF, PI3K-Akt, and VEGF signaling pathways; and axon guidance (Fig. 4E). Taken together, the enriched gene sets all...
KEGG: Kyoto encyclopedia of genes and genomes LDF: Laser doppler flowmetry LSCI: Laser speckle contrast imager MMPs: Matrix metalloproteinases NAWM: Normal appearing white matter NVU: Neurovascular unit NWO: Netherlands Organisation for Scientific Research ...
The KEGG pathway analysis results indicated that ribosome and ribosome-related pathways were highly associated with ovarian development at stage II across both transcriptomes, likely to support the subsequent vitellogenesis by providing the necessary materials. Additionally, the neurodegeneration, MAPK, cAMP ...
目的探究miR-424介导的血管内皮生长因子(VEGF)A低表达对宫颈鳞状细胞癌的侵袭和转移的影响.方法建立宫颈癌裸鼠抑制瘤模型,30 d后检测肿瘤体积,肿瘤重量;qPCR检测miR-424表达水平;免疫组化检测Ki67,VEGFA阳性表达率;荧光素酶报告实验验证miR-424-5p与VEGFA靶向关系;将VEGFA构建到腺病毒LV中过表达,SiHa细胞用miR-424...
(B) KEGG pathway enrichment analysis showing genes involved in PI3K/AKT signaling pathway and cytokine–cytokine receptor interaction were the largest in DXM + GM enema treatment mice compared with ARP mice. Full size image DXM + GM enema ameliorates inflammation by inhibiting NF-κB ...
(HCM) KEGG mmu05414 Dilated cardiomyopathy KEGG mmu04020 Calcium signaling pathway KEGG mmu04260 Cardiac muscle contraction KEGG mmu04960 Aldosterone-regulated sodium reabsorption KEGG mmu04340 Hedgehog signaling pathway KEGG GO:0022626 Cytosolic ribosome GOCC GO:0044391 Ribosomal subunit GOCC GO:0022625 ...
3c). A total of 88 pathways were obtained by KEGG pathway analysis. The results indicated that XLLXF may play an anti-TNBC role, mainly through cancer-related pathways, PI3K/Akt signaling pathways, TNF signaling pathways, HIF-1 signaling pathways, MAPK signaling pathways, and VEGF signaling ...