VEGF-2 receptor and protein tyrosine kinase inhibitors and pharmaceutical use thereofThe invention relates to compounds of general formula (I) wherein W, D, E, G, J, L, R, R, R, R, Rand Y are as defined herein, and pharmaceutically acceptable salts, hydrates, or solvates thereof, for ...
Novel vegf-2 receptor and protein tyrosine kinase inhibitors and pharmaceutical use thereofThe invention relates to compounds of general formula (I) wherein W, D, E, G, J, L, R 1 , R 2 , R 3 , R 4 , R 5 and Y are as defined herein, and pharmaceutically acceptable salts, ...
上海玉博生物科技有限公司 主要致力于“HTScan(R) VEGF Receptor 2 Kinase Assay Kit CST 7788”的生产销售。多年的“HTScan(R) VEGF Receptor 2 Kinase Assay Kit CST 7788”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司经营的产品名称深受广大用户信
英文别名:Vascular endothelial growth factor receptor 2, KDR, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1 描述:Recombinant Human Vascular Endothelial Growth Factor Receptor 2 is produced by our Mammalian expression system and the target...
(kinase-insert-domain-containing receptor) proteins have been shown to bind VEGF with high affinity. In vitro, VEGF is a potent endothelial cell mitogen. In cultured endothelial cells, VEGF can activate phospholipase C and induce rapid increases of free cytosolic Ca2+. VEGF has been shown to ...
kinase?inhibitor (EGFR-TKI)；Chemotherapy 据2015年中国相关部门的流行病学调查结果，肺癌在我国各个地区的发病率和死亡率均居恶性肿瘤首位，而且其患病人数在以每年近80万人次的速度持续增加，由于我国居民健康意识和癌症早筛观念相对滞后，肺癌确诊时往往已经晚期，其中农村地区表现尤为突出，肺癌中非小细胞 肺癌(NSCLC...
VEGF RECEPTOR TYROSINE KINASE INHIBITOR COATED STENTThe invention relates to the local administration of a vascular endothelial growth factor receptor tyrosine kinase inhibitor or a pharmaceutically acceptable salt, optionally in conjunction with one or more other active ingredients, and a device adapted ...
VEGFR2, Phosphorylated (Tyr1054) (Vascular Endothelial Growth Factor Receptor 2, VEGF Receptor 2, VEGFR 2, VEGFR-2, VEGFR, CD309 Antigen, Fetal Liver Kinase 1, FLK1, Kinase Insert Domain Receptor, KDR, KRD1, Ly73, Protein Tyrosine Kinase Receptor FLK1) (FITC)化学性质...
As caspase-8 can also be activated by other mechanisms independent of death receptor activation [39, 40], we sought to determine whether the mechanism of endostatin-induced apoptosis of endothelial cells was caspase-8 dependent. We thus examined the expression of caspase-8 following treatment of ...
is a type III receptor tyrosine kinase. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of FLK1 (VEGF Receptor 2) are implicated ...