The 5'UTR-specific mutation in VEEV TC-83 genome has a strong effect on RNA replication and subgenomic RNA synthesis, but not on translation of the encoded proteins. Virology 387:211-21.Kulasegaran-Shylini R., Thiviyanathan V., Gorenstein D. G., Frolov I. 2009. The 5′UTR-specific ...
Using a mouse model for 尾-amyloidosis, Tg2576 mice, we found that cognitive deficits and brain pathology were more severe in Tg2576 mice infected with VEEV TC-83 compared to mock-infected controls. Thus, during immune activation, the kynurenine pathway plays a more active role in the VEEV ...