VCCI - IP CO., LTD. Office Address: 8th Floor, VCCI Building, 9 Dao Duy Anh, Hanoi, Vietnam Postal Address: P.O.Box 608, 1 Le Thach, Hanoi, Vietnam Tel:(+84)24 3577 1365 Fax:(+84)24 3577 1563 (+84)24 3577 2595 (+84)24 3577 2596 ...
VCCI – IP CO., LTD. Office Address: 8th Floor, VCCI Building, 9 Dao Duy Anh, Hanoi, Vietnam Postal Address: P.O.Box 608, 1 Le Thach, Hanoi, Vietnam Telephone: +84-24-3577-1365 Facsimile: +84-24-3577-1563; +84-24-3577-2595; +84-24-3577-2596; +84-24-3577-2629; E-mail...
vMIP-IIMIP-1 beta/CCL4molecular dynamicsCertain viruses have the ability to subvert the mammalian immune response, including interference in the chemokine system. Poxviruses produce the chemokine binding protein vCCI (viral CC chemokine inhibitor; also called 35K), which tightly binds to CC ...
Molecular dynamics were then used to compare the vCCI:vMIP-II complex with the known vCCI:Macrophage Inflammatory Protein-1β/CC-Chemokine Ligand 4 (MIP-1β/CCL4) complex. The simulations show key interactions, such as those between E143 and D75 in vCCI/35K and R18 in vMIP-II. Further,...
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