Vc-MMAD consists the ADCs linker(Val-Cit) and potent tubulin inhibitor (MMAD), Vc-MMAD is an antibody drug conjugate. ChemeGen 作为优秀的抑制剂、激动剂及新型生命科学试剂的供应商,致力于为广大科研、商业实验室的科学研究者提供高品质的产品与技术服务,不断促进生命科学领域的新技术发展。 公司简介 ...
应用领域 13-十四炔酸作为一种PROTAC linker,主要用于合成PROTAC分子。PROTAC是一种新型的蛋白质降解靶向药物(proteolysis-targeting chimera),通过别构效应激活E3泛素连接酶,从而降解特定的蛋白质目标。 结构式: Alkynyl Palmitic Acid;99208-90-9 物理化学性质 分子式: C14H24O2 分子结构: 该物质是一种带有十四碳...
In a comparison of three different tissues, the membrane cytoskeleton linker protein ezrin was found to assume high levels of phosphorylation on threonine-... L Zhu,J Hatakeyama,C Chen - 《American Journal of Physiology》 被引量: 0发表: 2008年 ABSORPTION OF UPID BY THE SMALL INTESTINAL ENTERO...
This 40-page handbook features essential tools that Mass Spec Core Labs can utilize in order to offer their users reliable, consistent data. These kits and reagents have been fully tested to enable optimal outcomes, from protein digestion to peptide enrichment...
Notably, heme storage is observed in heme degrading protein MhuD of Mycobacterium tuberculosis in non-iron depleted situation31. Most siderophore and heme transporters are Type III PBPs. Although most of the Type III PBPs have a rel- atively stable bi-lobal arrangement with a linker helix, ...
抗体偶联药物(antibody-drug conjugate,ADC) 是通过一个化学链接将具有生物活性的小分子药物连接到单抗上,单抗作为载体将小分子药物靶向运输到目标细胞中。在设计上,ADCs一般包含三个部分,分别为抗体、细胞毒活性药物负荷和把两者连接起来的Linker,三者均对ADCs药物的疗效有着重要的影响和作用。
4 - 6 BLOCK-iT™ RNAi TOPO® Transcription Kit BLOCK-iT™ TOPO® Linker Kit and BLOCK-iT™ RNAi Transcription Kit: Dry ice BLOCK-iT™ RNAi Purification Kit: Room temperature BLOCK-iT™ TOPO® Linker Kit and BLOCK-iT™ RNAi ...
Vc-MMAD为抗体偶联药物(ADC),由Val-Cit作为linker,连接微管抑制剂MMAD。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途! CAS号:1401963-17-4 分子量:1369.71 储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。 培养操作步骤: 1.用盖片镊将盖玻片自75%乙醇中取出,用无菌丝绸布擦拭...
cVc1.1 is an engineered peptide in which a cyclizing linker (grey) was added to confer oral activity to the analgesic peptide Vc1.1. This peptide comprises two disulfide bonds, which are shown in orange. The substituted positions are shown in bold. The time-averaged backbone root-mean-square...
Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage A. D. Hershey, Martha Chase: Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage AD Hershey,M Chase 被引量: 114发表: 2017年 The H1 linker histones: multifunctional proteins beyond the...