12.1 Mechanism of Action Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle coupled to the Gq/11-phospholipase C-phosphatidyl-inositol-triphosphate pathway, resulting in the release of intracellular calcium. In addition, vasopressin stimulates antidiuresis via stimulatio...
In addition to a peripheral mechanism of action, the V1b receptor is expressed in hippocampal CA2 pyramidal neurons, and to some extent in the hypothalamus and the amygdala (Barberis and Tribollet, 1996; Hernando et al, 2001; Young et al, 2006). Although the large majority of studies ...
Evidence for the Importance of High-Valent FeO and of a Diketone in the Molecular Mechanism of Action of Antimalarial Trioxane Analogs of Artemisinin The syndrome of inappropriate secretion of antidiuretic hormone (ADH) occurred during an acute psychotic reaction in a patient who was taking no ...
Evidence for the Importance of High-Valent FeO and of a Diketone in the Molecular Mechanism of Action of Antimalarial Trioxane Analogs of Artemisinin The syndrome of inappropriate secretion of antidiuretic hormone (ADH) occurred during an acute psychotic reaction in a patient who was taking no ...