Exposure to fine particulate matter air pollution (PM2.5) is associated with acute atherosclerotic cardiovascular (CV) events.The risk for myocardial infarction increases by as much as 48% within 2 hours for every 25 μg/m~3 increase in ambient PM2.5 concentration.Automobile sources may be ...
3.In the arterial system, vasodilation and vasoconstriction of the arterioles is a significant factor in systemic blood pressure: Slight vasodilation greatly decreases resistance and increases flow, whereas slight vasoconstriction greatly increases resistance and decreases flow. ...
increases the myocardial oxygen demand (partially compensated for by a rise in aortic root pressure, increasing coronary artery flow) and, in combination with the lowered heart rate, causes a fall in cardiac output. Mesenteric and renal arteries may be constricted, but renal blood flow may ...
Increased blood flow and vascular leakage of proteins preferentially affect tissues that are sites of diabetic complications in humans and animals. These v... JA Corbett,RG Tilton,K Chang,... - 《Diabetes》 被引量: 1434发表: 1992年 Review of Alterations in Endothelial Nitric Oxide Production in...
Also, bolus injections of noradrenaline (0.75, 1.5 and 3 nmol/kg) (Fig. 2B, E and H) or angiotensin II (50, 100 and 200 pmol/kg) (Fig. 2C, F and I) induced dose-dependent increases in blood pressure. The blood glucose level in each infusion group was almost constant throughout ...
Several biochemical studies indicate that hypertension produced by administration of deoxycorticosterone acetate (DOCA) plus saline as the drinking fluid is accompanied by significant increases in catecholamine turnover rates and a decrease in catecholamine content of peripheral tissues. In the present study...
Gallbladder distension in anesthetized pigs reflexly increases heart rate and arterial pressure by means of afferent vagal pathways and efferent sympathetic mechanisms. The effect of such distension on the coronary circulation is unknown. The present study was undertaken to determine whether gallbladder ...
4). Moreover, the vasopressor effects of phenylephrine were not affected by PE or LPS, but showed significant increases in PE/LPS female kidneys (Fig. 5). Figure 2 Effect of PE programming on cumulative vasoconstrictor response curves of Ang II (A) and AUCs of the Ang II cumulative vaso...
Decreased microvascular blood flow (MBF) increases the likelihood of vaso-occlusion by increasing entrapment of sickled red blood cells in the microvasculature. Because those with SCD have dysautonomia, we anticipated that thermal exposure would induce autonomic hypersensitivity of their microvasculature ...
[64]. The sympathetic nervous system might be more excitable in cold weather and thus aggravate a pre-existing sympatho-vagal imbalance and thus induce cerebral vasoconstriction. It has been shown that cerebrovascular resistance increases during cold face stimulation [65] and sympathetic stimulation ...