Disialoganglioside GD3-synthase over expression inhibits survival and angiogenesis of pancreatic cancer cells through cell cycle arrest at S-phase and disr... Gangliosides play important roles in the development, differentiation and proliferation of mammalian cells. They bind to other cell membrane compo...
[14]. These polymers degrade via hydrolytic cleavage at the ester bond, producing fragments of diminishing molecular weight. Macroscopically, the degradation of these materials is evidenced first by a loss of mechanical properties, followed by a decrease in mass/volume. In the final phase ofin ...
A complicated well-regulated balance exists between the thrombosis and fibrinolysis systems. This chapter will cover the two main categories of retinal vascular occlusive disease (RVOD): central (CVO) or branch retinal vein occlusion (BVO) and central (C
much more difficult. Due to this, during the distribution phase, nanomaterials accumulate more evident in vascular defect area and have a high permeability [23]. Hence, size is vital for the design and synthesis of nano delivery systems. In addition to the passive targeting strategy, active targ...
We recently identified the acute-phase protein fibrin(ogen) as a critical adhesive ligand involved in platelet migration in vitro16. Indeed, when we examined the inflamed cremaster microvasculature, we detected a thin layer of fibrin(ogen), providing a two-dimensional platform for adhesion of ...
The potential leukemogenic myelosuppressive agents busulfan and hydroxyurea and the nonleukemogenic cytosine interferon-伪 have proven to be effective in the control of the proliferative phase of polycythemia vera. However, data on the natural history of polycythemia vera and the best ...
[107] reported PKCδ translocation in the early phase of lipid accumulation in oleic acid (OA)-induced RAW264.7 macrophages. Ma et al. [108] also demonstrated that PKCδ mediates cholesterol accumulation in PMA-activated macrophages. Scavenger receptor class A (SR-A) and CD36 play vital roles...
A single cell in culture has its own oscillation rhythm, whereas cell populations in in vitro culture are usually arrhythmic because of the asynchronous circadian rhythm among cells.12 However, once a phase-aligning stimulus such as 50% serum is applied, they start to show uniform circadian ...
Disadvantages of radial access include a higher incidence of procedure failure that necessitates resorting to the femoral approach, longer procedural times (at least in the ‘learning curve’ phase), postprocedural radial artery spasm and occlusion [29]. Ra...
[27]. Briefly, tests were conducted in a quiet, temperature-controlled room between 9 and 11 a.m. after at least 30-minute rest, using recommended QRS-gated brachial artery diameter measurements done in end-diastolic phase, which corresponds to the onset of the R wave. Ultrasound examinations...