The rationale for the use of these molecules for the treatment of COVID-19 is connected to the role of the JAK-STAT signaling pathway in the biosynthesis of cytokines [102] Indeed Regarding the docking pose of baricitinib and Mpro complex, the ligand has ten interactions with the amino acid...
Streptomyces coelicolor and Streptomyces lividans constitute model strains to study the regulation of antibiotics biosynthesis in Streptomyces species since these closely related strains possess the same pathways directing the biosynthesis of various antibiotics but only S. coelicolor produces them. To get a...