This patent provides coverage for the use of volume changing battery cells, including the company's proprietary Ecell, to drive drug-delivery devices in order to administer drugs to patients via various routes of administration wherein the delivery rate can be very precisely controlled by an electr...
These innovative systems are applied to overcome the challenge of reduced water solubility that may improve the drug accessibility, sustained release, and high metabolic stability. The prime emphasis of this review is particularly on the universal routes of drug administration through...
The pharmacotherapeutic effects of prostaglandin E2 (PGE2) and 15 (S) 15-methyl PGF2伪 given by different routes of administration, were studied in 20 norm... M.A. El-Gendi and S.H. Nassar and M. Toppozada and F. Abdel-Raheem - 《Prostaglandins》 被引量: 37发表: 1982年 加载更多来...
Fig. 7: Delivery methods and administration routes for RNA-based drugs. a The three major delivery methods for RNA-based therapeutics in mammalian cells. Naked RNAs can be recognized by receptors that are broadly expressed across various cell types, or they can be conjugated with a compound reco...
The transappendageal pathway seems to be less important for nerol (55% to 82% of the absorption routes between 4 h and 32 h) and azone (60% to 79% of the absorption routes until 32 h) than for propylene glycol (63% to 96% of the absorption pathways during the whole experiment), ...
15, Pages 5852-5873: Nanoparticle-Mediated Pulmonary Drug Delivery: A Review Colloidal drug delivery systems have been extensively investigated as drug carriers for the application of different drugs via different routes of administration. Systems, such as solid lipid nanoparticles, polymeric nanoparticles...
Oral administration has always been considered one of the best administration routes, however some poorly soluble small molecule drugs and macromolecular proteins, peptides, and nucleic acid drugs can be limited by degradation or being difficult to absorb in the gastrointestinal tract, making their oral...
Bocci V, Zanardi I, Michaeli D, Travagli V: Mechanisms of action and chemical-biological interactions between ozone and body compartments: a critical appraisal of the different administration routes. Curr Drug Ther. 2009, 4: 159-173. 10.2174/157488509789055045. Article CAS Google Scholar Travagli...
Besides oxygen, several other gases such as NO, CO, H2, H2S, Xe and O3 have come to age over the past few years. With regards to O3, its mechanisms of action in medicine have been clarified during the last two decades so that now a comprehensive framewor
Recently, intranasal drug delivery has become more popular due to its unique and favourable characteristics, providing potential advantages over other routes of drug administration in the management of canine SE. This narrative review provides an outline of the management of SE at home and in a ...