RNA therapy refers to the treatment or prevention of diseases using RNA-based molecules. The recent advent of a series of effective messenger RNA-based vaccines in response to the COVID-19 pandemic has reignited research interest in RNA therapy. Based on
Primary liver cancer, which is scientifically referred to as hepatocellular carcinoma (HCC), is a significant concern in the field of global health. It has been demonstrated that conventional chemotherapy, chemo-hormonal therapy, and conformal radiotherapy are ineffective against HCC. New therapeutic app...
Information about children born, detected cases of CAH was taken from statistic form № 12 "Information on the number of diseases, detected within patient residing in the service area of medical organization, Rosstat" during 2006–2018yrs. Materials for analysis of health clinic of children's CAH...
which are located in the lamina propria of the respiratory tract, gastrointestinal tract, urogenital tract, and other mucous membranes. After synthesis, one J chain connects two monomer IgA to form dimer IgA (dIgA). After the formation of dIgA...
Peptide vaccines are the simplest form of nano-sized vaccine, which can be easily administrated at specific tissue and cell of interest by loading with appropriate nano vehicle [253]. Previously it had been established efficacy in SERS, MERS, influenzas and other chronic diseases like cancer [254...
form dimer IgA (dIgA). After the formation of dIgA, it is secreted from plasma cells and forms a dIgA–pIgR complex with the polymeric immunoglobulin receptor (pIgR) expressed by epithelial cells [2]. Subsequently, under the action of proteolytic enzymes, the extracellular segment of pIgR, ...
Statistical analysis. We used STATA 12.0 software (Stata Corporation, College Station, TX, USA) to per- form all of the statistical analyses. The extracted HRs and their corresponding 95%CIs were comprehensively calculated to obtain pooled HRs and 95%CIs. If the pooled HR > 1 ...
Forty percent of lung cancers are lung adenocarcinomas (LUAD), a common histological subtype of non-small cell lung cancer (NSCLC). More than 200 nucleotides make up a form of RNA known as lncRNAs. It is known that lncRNAs regulate many biological processes in a crucial way. More ...
The level of phosphorylated form of Akt was lower after MSC-EV treatment when compared to vehicle-treated group (Additional file 1: Fig. S8). Taken together, MSC-EV treatment stimulates NO production in ischemic tissues, which may be involved in NO-mediated angiogenesis in injured tissues. MSC...
ESWT is a non-invasive treatment form of physical therapy that applies tension and compression to tissue cells by passing through various mediums, which originates from extracorporeal shock wave lithotripsy (ESWL) [14]. ESWT systems can be categorized into three types based on their sound sources...