The TNFSF15-initiated TNF receptor-associated factor 2/receptor-interacting protein kinase 1/RIP3 pathway was required for mitogen-activated protein kinase and nuclear factor-κB activation, and, in turn, induction of each of the antimicrobial pathways; the TNFSF15-initiated Fas-associated protein ...
Targeted sequencing of 409 genes in tissue samples of 18 long-standing UC subjects at high risk of colorectal carcinoma (UCHR) was performed to identify somatic driver mutations, which may be involved in the molecular changes during the transformation of non-dysplastic mucosa to high-grade dysplasi...
Considerable efforts have been made in non-human species to understand the gene regulation of neural crest and found many important regulators, regulations, and pathways.FGFs andWNTinhibitors,Tfap2,Sox2/3were responsible for induction and formation of the neural plate border8,9,10,11,12,13.Foxd...
The most significant SNP (rs9540488) by childhood socioeconomic status interaction within the rs9540493 gene/region was suggestively replicated in the Multi-Ethnic Study of Atherosclerosis (MESA) (p = 0.07). Keywords: gene-environment interaction; body mass index; social/psychosocial factors; ...