mediated decay, protein modeling, RNA analysis, and splicing. We also have specialized internal expert panels by therapeutic area for oncology, cardiology, and neurology. These groups are committed to utilizing gene-disease specific guidelines and criteria with a deep expertise in variant classification...
Version: Available or changed with runtime version 1.0 until version 8.0 where it was deprecated for the following reason: "The property IsDataClassificationType is being deprecated. Use the property IsDataClassification instead."Indicates whether an AL variant contains ...
A relatively stable pattern of LOH (65.4%) of WT allele for PV tumors was observed, while the allelic balance (63%) or loss of variant allele (15%) was generally seen for carriers of BV. LOH data is a useful complementary argument forvariant classification.npj Breast Cancer...
classification of dangerous goods which largely adopts the classification system [...] legco.gov.hk 第55號法律公告的主要特點包括新 的危 險品分類,該 分類大體上是根據《國際海運危險貨物規則》("《國際規則》") 的分類方法,同時亦引入有關以消費品形式包裝的危險品的新 概念,訂明市民經常使用而以消...
Identifying pathogenic variants from the vast majority of nucleotide variation remains a challenge. We present a method named Multimodal Annotation Generated Pathogenic Impact Evaluator (MAGPIE) that predicts the pathogenicity of multi-type variants. MAG
To describe a system for the classification and nomenclature of HPV viral variants and provide landmarks for the numbering of nucleotide positions. The complete 8 kb genomes of the alpha-9 species group and HPV6 and 11 types, collected from isolates throughout the world were obtained from ...
The World Health Organization declared the recently discovered B.1.1.529 strain of the COVID-19 virus to be a variant of concern on November 26 and renamed it Omicron. The classification puts Omicron into the most-troubling category of COVID-19 variants, along with the globally dominant Delta...
. However, as the resolution of technologies used to identify these variants have improved, this classification has become one of nomenclature rather than practicality, and it is becoming clear that individuals can harbour changes in genetic content in a continuous scale from 1 bp to several Mb...
2 and summarized in the second through the fourth columns in Table 1, we provide the three product substitution classification criteria: substitution mechanism, substitution decision maker, and direction of substitutability. The term, substitution decision maker, is adopted to indicate the active party ...
The baseline morphological stage of CP was categorized by Cambridge classification. Clinical outcome variables included frequency and severity of pain episodes, presence of exocrine failure (defined by presence of steatorrhea and/or fecal elastase < 200 ug/g), and diabetes. The genetic tests included...