Bayesian modeling can be used to estimate a patient's vancomycin clearance (CLvanco) and volume of distribution (Vd) on the basis of one single vancomycin level either at steady state or even after one single dose. Bayesian modeling is a mathematically complex process that involves the following...
This calculator assumes that the vancomycin trough is drawn at steady state, which occurs prior to the fourth vancomycin dose (assuming a consistent dose and dosing regimen).3 Population Estimate of VdBy default, this calculator suggests a population estimate volume of distribution (Vd) of 0.7 L...
Dosing by Random Levels Calculator:This calculator uses a population Vd to calculate Ke based on a random level. The results are limited to calculating a one-time dose rather than a maintenance dose.
The average vancomycin dose was 37 mg/kg/day with median (range) duration of 7 (4 - 45) days. Acute kidney injury was identified in 2.1% of patients. Target AUC was achieved in 78% of cases. The average duration of culture positivity was 2.2 days, and no patients exhibited recurrent ...
This calculator uses a variety of methods to estimate a patient’s elimination constant (Kel), and uses published pharmacokinetic equations to estimate the most appropriate dose in order to achieve a specified vancomycin goal (either AUC:MIC or a trough level). By default, all doses are ...
To be best prepared to dose vancomycin you will need to: 1. Bring paper to write on and with 2. Bring a scientific calculator 3. Bring equation sheets 4. Review notes from kinetics course work 5. Review vancomycin dosing protocol (Note: this last item will be published following your kine...
percentage of vancomycin concentrations that could be used to calculate the AUC (i.e., for 2-level monitoring, two concentrations drawn within the same dosing interval and not during the vancomycin infusion), number of vancomycin dose changes per vancomycin-day, and incidence of acute kidney inju...
This calculator assumes that the vancomycin trough is drawn at steady state, which occurs prior to the fourth vancomycin dose (assuming a consistent dose and dosing regimen).3 Population Estimate of VdBy default, this calculator suggests a population estimate volume of distribution (Vd) of 0.7 L...