Valproic acid overdose.The article describes the case of a 19-year-old who developed a deep coma imitating brain death and other toxicities after taking an overdosage of valproic acid.EBSCO_AspReactions Weekly
route and dosage not stated]. A volatile alcohol screen reported 17 mmol/L of a compound with the same retention time as diethylene glycol [DEG]. It was subsequently discovered that a component of valproic acid capsules was incorrectly identified by the software as DEG....
Valproic acid dosage should be increased slowly and with regular monitoring for fluid and nutritional intake ( 5.14) Adverse Reactions/Side Effects Most common adverse reactions (reported >5%) are abdominal pain, alopecia, amblyopia/blurred vision, amnesia, anorexia, asthenia, ataxia, bronchitis, ...
STAVZOR (valproic acid) delayed release capsules are administered orally, and must be swallowed whole. As STAVZOR dosage is titrated upward, concentrations of clonazepam, diazepam, ethosuximide, lamotrigine, tolbutamide, phenobarbital, carbamazepine, and/or phenytoin may be affected [seeDRUG INTERACTION...
¿Cuál es la información más importante que debo saber sobre valproic acid? Valproic acid puede causar insuficiencia del hígado que puede ser fatal,especialmente en niños menores de 2 años, y en las personas con ciertos trastornos genéticos. ...
valproic acid was associated with other antiepileptic drugs (Rasalam et al., 2005). In a large population-based study on Danish people,Christensen et al. (2013)found 508 children exposed in utero to valproic acid and 2136 to other anticonvulsant drugs over a total of 655,615 eligible ...
Few treatment episodes coincided with contraceptive use (37 012 [22.3%]), and oral dosage forms were the most common (27 069 [73.1%]). Conclusions and Relevance In this cohort study of patients of childbearing age who used valproic acid, pregnancy rates during valproic acid use d...
Valproic acid (VPA) is one of the commonly used broad-spectrum anti-seizure medications (ASMs) in clinical practice, often used as an initial treatment and monotherapy in the real world [3]. Therefore, its adverse drug reactions (ADRs) have always been a concern among medical practitioners [...
Dosage form 500mg/kg/day, intraperitoneal injection, for 30 days Applications Valproic acid induced growth inhibition of human ovarian cancer transplanted subcutaneously in nude mice. Moreover, valproic acid (50 mg/kg, IV infusion) decreased pro-inflammatory cytokine gene expression in a canine endot...
Bioavailability of Valproic Acid Under Fasting/ Nonfasting Regimens over studies under fasting conditions, and one open-label, randomized, single-dose, three-period crossover study under fasting and nonfasting conditions. ... A.,H.,C.,... - 《Journal of Clinical Pharmacology》 被引量: 11发表...