All the parameters were validated as per ICH guidelines and found to be suitable for routine analysis of drug in pharmaceutical dosage form.doi:10.22270/jddt.v9i4.3127Santosh Vilaschand GandhiAkshay Pramod SanklechaJournal of Drug Delivery and Therapeutics...
All the analytical validation parameters were determined and found in the limit as per ICH Guidelines which indicate the validity of the method. The developed method is also found to be precise and robust for the simultaneous determination of Fluconazole and Ivermectin in tablet formulation....
The high-performance liquid chromatographic separation was performed at the flow rate 1.0min/mL, UV detector wavelength 250nm and pH of the buffer 3.0 as optimized parameters using design of experiments. The retention time values of valsartan were found to be 10.177min. Percent recovery in terms ...
The method was validated as per the International Conference on Harmonization (ICH) guidelines as well as for the robustness studies the Quality by Design approach used based on 3-Level Factorial Design of Experiment. On the basis of Designs the three chromatographic parameters (Flow Rate, pH and...
The method was validated as per the various parameters given in ICH guidelines (ICH guidelines, 1996). The linearity was studied in the concentration range of 100–600 ng/spot of Drotaverine hydrochloride and 200–600 ng/spot of Omeprazole, respectively. Precision of the method is expressed ...
The developed method was validated as per ICH guidelines [13-14] for its accuracy, linearity, precision, specificity, robustness, ruggedness, limit of detection and limit of quantification by using the following procedures. The parameters are validated as shown in table 9. System suitability ...
e system suitable parameters such as tailing factor (1.5) and number of theoretical plates (2365) are found to be within the limits. e retention time of the component was found to be 2.647 min. e intraday precision or interday precision of a method was expressed in terms of statistical ...
ParametersLAMINH 246 nm272 nm246 nm272 nm Beer’s law limit (μg/mL) 5–30 5–30 5–30 5–30 Absorptivity 287 435 288 276 Regression equation (y = mx + c) Slope (m) Intercept (c) 0.0279 0.0079 0.0405 0.0191 0.0267...
The method was further validated as per ICH M10 guidelines using C-18 reverse phase column. Fisetin was used as an internal standard. Gradient elution was carried out at a flow rate of 1 mL/min in acetonitrile (ACN) and 2% glacial acetic acid (GAA). The chromatograms of all three phyto...
Firstly, the Sleepiz One+ improves patient comfort during the monitoring of respiratory parameters. Devices such as thoracic respiratory effort bands and nasal cannulas are intrusive and inconvenient. Secondly, the improved comfort, enables long-term respiration monitoring that provides HCPs a more ...