Tumor vaccines aim at reversing tumor-induced immunosuppression by eliciting high-avidity T cells directed against subdominant epitopes of tumor antigens. Peptide-based cancer vaccines are particularly well suited for use in the clinic because they are known to be safe, specifically target a definite ...
Therapeutic cancer vaccines have undergone a resurgence in the past decade. A better understanding of the breadth of tumour-associated antigens, the native immune response and development of novel technologies for antigen delivery has facilitated improve
Development of vaccines for the treatment of cancer has posed many challenges, but results from some recent studies have confirmed the potential for clinical benefit Progress has been driven by advances in our understanding of cancer immunology and, in particular, the nature and dynamics of the tumo...
Immunotherapy for non-small cell lung cancer: are we on the cusp of a new era? In this editorial, we highlight the exciting advances in immunotherapy for the treatment of non-small cell lung cancer, with nivolumab being the first immu... SN Waqar,D Morgensztern - 《Expert Review of Cli...
治疗的疫苗,treatment vaccines or therapeutic vaccines【免疫疗法】 治疗机制: Cancer treatment vaccines boost the immune system's ability to find and destroy antigens. Often, cancer cells have certain molecules called cancer-specific antigens on their surface that healthy cells do not have. When a ...
Track 2: Cancer, Malaria & TB Vaccines Malariacontinues to claim an estimated 2 to 3 million lives annually and to account for untold morbidity in the approximately 300 to 500 million people infected annually. Malaria is considered are-emerging disease, due largely to the spread of drug-resistan...
mRNA vaccines in cancer immunotherapy: clinical benefits, limitations, and future The emergence of immunotherapy has created new opportunities for the treatment of cancer, which has been one of the main causes of death in the world. mRNA... S Yang 被引量: 0发表: 2023年 Personalized tumor vacc...
The creation of therapeutic cancer vaccines has solid biological and preclinical rationales, however, it has been difficult to translate this treatment approach into the clinical therapies. Immunotherapy has gained widespread attention as an emerging tool for cancer treatment. Among them, cell-based ...
Therapeutic vaccines could provide a transformative shot in the arm for cancer treatment. Liam Drew Outline|27 March 2024 How does a cancer vaccine work? After decades of slow progress, therapeutic vaccines that direct the immune system to attack tumours could soon become a fixture of cancer treat...
Induced pluripotent stem cells(iPSCs)can be generated via reprogramming ofsomatic cells into pluripotent stem cells by introducing defined factors with appropriate culture conditions. iPSCs have 4 key properties. iPSCs have pluripotency and selfrenewal ability, which are properties in common with ...