Adjuvants are key components of many vaccines, used to enhance the level and breadth of the immune response to a target antigen, thereby enhancing protection from the associated disease. In recent years, advances in our understanding of the innate and adaptive immune systems have allowed for the ...
cellular and humoral immunity [4,5], underscores the pivotal role of mRNA vaccines in tumor-targeted therapy. In recent decades, great strides in experimental techniques have catalysed the widespread utilization of mRNA vaccines across diverse domains, with an emphasis on tumor-targeted therapy. Curre...
Cancer vaccination cascade The cancer vaccine cascade can be encapsulated in five processes, which are as follows: antigen delivery aimed at LNs, antigen/adjuvant co-encapsulation, specific antigen identification, antigen internalization and release, and antigen cross-presentation for T-cell cross-priming...
Intralymphatic immunotherapy and vaccination in mice JoVE, 84 (2014), Article e51031 View in ScopusGoogle Scholar 180 C. Guo, M.H. Manjili, J.R. Subjeck, D. Sarkar, P.B. Fisher, X.Y. Wang Therapeutic cancer vaccines: past, present, and future Adv Cancer Res, 119 (2013), pp. 42...
Vaccination is the principal means used to control and treat porcine reproductive and respiratory syndrome virus (PRRSV) infection. An array of PRRS vaccin... Michael,P.,Murtaugh,... - 《Vaccine》 被引量: 198发表: 2011年 Novel strategies and approaches to develop the next generation of vaccin...
The pivotal role of type 1 conventional dendritic cells (cDC1s) in the field of dendritic cell (DC)-based tumor immunotherapies has been gaining increasing recognition due to their superior antigen cross-presentation abilities and essential role in modul
Cancer vaccination cascade The cancer vaccine cascade can be encapsulated in five processes, which are as follows: antigen delivery aimed at LNs, antigen/adjuvant co-encapsulation, specific antigen identification, antigen internalization and release, and antigen cross-presentation for T-cell cross-priming...
Blood of different pigs were sampled to determine the levels of cell- immunity and humoral-immunity at 0, 20, 40 and 50 days after primary vaccination. The results showed that transforma-tion rate of T lymphocyte in polysaccharides groups was 61.4%, 65.0%, and 63.4%, respectively, which ...
They have been proven to be effective in preventing infections that previously had high morbidity and mortality. An example of this is the eradication of small pox, which was mainly attributed to successful vaccination programs. Preventing a high burden disease has since proven to be a cost ...
146 Various triple combinations of cancer vaccines with CPIs and costimulator agonist antibodies are also being explored. Vaccination with an adenovirus-based vaccine delayed tumor growth in 30–40% of mice, while vaccination in combination with anti-CD40 and anti-CTLA-4 antibodies induced complete ...