Prior to their participation in the study, all of the participants signed a consent form, confirming their willingness to participate in the research. Consent to publish All participants provided their consent for their anonymized data to be presented in scientific conferences, journal articles, and ...
Study design and patient characteristics This single-arm and single-center clinical trial evaluated the safety and feasibility of personalized neoantigen vaccines for the treatment of MSS–CRC patients with postoperative recurrence or metastasis. In this study, the safety and feasibility of personalized ne...
For clinical studies, a statement of informed consent having been obtained from a patient or their nominated representative, paired with ethical approval for the study from a suitable institution, as required by the policies of the journal, may be considered sufficient evidence, but the journal ...
Beyond confirming patient safety, the Phase 1 trial is intended to determine the optimal dose of the drug before initiating larger Phase 2 and 3 trials. “You have to start somewhere, and just to get to a Phase 1 trial, many drugs fall by the wayside. And if patients re...
Readability assessment of online ophthalmic patient information. JAMA Ophthalmol. 2013;131(12):1610-1616. doi:10.1001/jamaophthalmol.2013.5521 PubMedGoogle ScholarCrossref 7. Readable. Accessed March 31, 2021. https://readable.com/ Informed Consent—We Can and Should Do Better JAMA ...
330 This emphasizes the importance of a trusting doctor-patient relationship and providing parents with tailored information in advance of their child's immunizations; in this manner their questions are answered and they are prepared with the facts when they encounter contrary information from other ...
The protocol of the GT-30 clinical study was approved by the institutional review board or ethics committees at each participating institution. Written informed consent was obtained from each patient. The study was registered athttps://clinicaltrials.gov/under the identifierNCT04251117. The trial was...
Measles Outbreak Traced to Fully Vaccinated Patient for First TimeGovernment and Corporate propaganda suggests there is no reason why anyone should have doubts about vaccines, they are 100% effective and can never cause harm. Propaganda is however the tools authoritarianism uses when the truth is ...
When the results of this study were published three years later in the journal Pediatrics, the problem had been fixed, in that by adding another set of data from a third HMO, reorganizing the criteria for inclusion and restructuring the patient groupings, a less than statistically significant li...
‘what-if’ scenarios to determine the best dosing strategies for various patient cohorts, such as the elderly and children. Many global pharmaceutical companies have also used the Vaccine Simulator, and its findings have been presented to regulatory agencies, including a U.S. Food and Drug ...