In studying the question of specific therapeutics it is important to bear in mind, in the first place, the fundamental distinction between passive and active immunity. In the utilization of passive immunity in the cure of disease, aid to the individual comes from without. Moreover, the ...
the antibody-producing cells, called B cells (or B lymphocytes), remain sensitized and ready to respond to the agent should it ever gain entry to the body. A vaccine may also confer passive immunity by providing antibodies or
In southern Italy, 44 contacts of hepatitis B virus carriers, including infants of carrier mothers, became HBsAg positive despite passive and active immuni... WF Carman,P Karayiannis,J Waters,... - 《Lancet》 被引量: 2389发表: 1990年 Efficacy of BCG vaccine in the prevention of tuberculosis...
Also, central clearance of Aβ, i.e., at the brain, has other potential complications—particularly if the antibodies are against the N-terminal region or B-cell epitope—problems that can occur with passive or active immune therapy, i.e., mAbs or vaccination (Liu et al., 2014)...
The author has studied the time of onset of active immunity in the mouse, and of the appearance of protective antibodies in the blood of the rabbit, following the inoculation of various types of pneumococcus antigen. In conformity with the results recorded by the great majority of workers he ...
21-4).298 Following unblinding of the study after 15 months of active observation, passive surveillance continued for 3 additional years, during which vaccine efficacy ranged from 77 to 92% for the bivalent vaccine and from 65 to 82% for the monovalent vaccine, depending on the case definition...
immunity, recombinant vaccines are administered with an adjuvant [4,8,23]. The newly developed vaccines consisting of only the most immunogenic protein(s) of infectious organisms can eliminate the risk of active infection of live attenuated vaccines or inactivated vaccines, particularly due to ...
Passive immunization of cyno- molgus macaques with immune sera or a pool of neutralizingmonoclonat antibodies failed to protect against challenge with SIVmac251. AIDS Res Hum Retroviruses 10:18%194; 1994. 70 Kindt TJ, Hirsch VM, Johnson PR, Sawasdi- kosol S. Animal models lbr acquired immu...
The strategy of an anti-cocaine vaccine is to prevent cocaine access to the brain, and hence, to prevent the ability of cocaine to reach the DAT in the caudate and the putamen. Two approaches, passive and active immunization, have been used to develop anti-cocaine immunotherapies. The small...
An individual can acquire immunity for a specific pathogen passively or actively. In passive immunization a person receives antibodies or lymphocytes that have been produced by another individual’s immune system; in active immunization the individual’s own immune system is stimulated to produce ...