Infections have important adverse consequences for older adults, particularly those who are frail. In this chapter, we review how age and frailty impact immune responses to infections and vaccines, including through immunosenescence and inflammaging. We discuss infections that are currently vaccine-preventa...
Fact Sheet for Recipients and Caregivers About the Moderna Covid-19 vaccine (2024-2025 Formula). Further information Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. ...
Understand the dynamics governing global vaccine markets & what interventions can be made for better access Influenza & Respiratory Latest updates in RSV, influenza, pneumococcal, pan- and combinational vaccines Vaccine Safety New tools to measure vaccine surveillance, safety and managing misinformati...
Respiratory Syncytial Virus Infection (RSV) – Older Adults are at High Risk for Severe RSV Infection Fact Sheet. https://www.cdc.gov/rsv/factsheet-older-adults.pdf.5 Centers for Disease Control and Prevention. RSV in Infants and Young Children. https://www.cdc.gov/rsv/high-ris...
Structures of both conformations have been determined for RSV F10–13, as well as for the fusion proteins from related paramyxoviruses, providing insight into the mechanism of this complex fusion machine14–16. Like other class I fusion proteins, the inactive precursor, RSV F0, requires cleavage ...
Another study compared liquid and lyophilized single vial formulations containing a soluble form of RSV protein—RSVsF to show that apart from a minimal increase in particle size after reconstitution of the lyophilized formulation, all the other physicochemical properties remain unchanged. Using BALB/c ...
Prior to administration of COVID-19 vaccine, adjuvanted (Novavax) (2024-2025 Formula), provide the vaccine recipient or their caregiver with information consistent with the Fact Sheet for Recipients and Caregivers: Emergency Use Authorization (EUA) of the Novavax COVID-19 Vaccine to Prevent Corona...
Experts at the meeting acknowledged rocky rollouts are far from unheard of for new vaccines, with other shots for RSV and pneumococcal bacteria also hitting snags in insurance coverage and availability this year. "There needs to be some stronger enforcement to put that in place, unless we're ...
RSV Transmission. https://www.cdc.gov/rsv/about/transmission.html. Updated December 18, 2020. Accessed November 18, 2022. 3 Centers for Disease Control and Prevention. Respiratory Syncytial Virus Infection (RSV) – Older...
Mucosal vaccine approaches for prevention of HIV and SIV transmission. Curr. Immunol. Rev. 15, 102–122 (2019). CAS Google Scholar Francica, J. R. et al. Thermoresponsive polymer nanoparticles co-deliver RSV F trimers with a TLR-7/8 adjuvant. Bioconjug. Chem. 27, 2372–2385 (2016)....