More recently, recombinant technology-derived purifiedsubunit vaccineshave been developed that consist of virus-like particles (VLPs) that self-assemble when theL1 proteinof HPV is produced in isolation of otherviral proteins(Fig. 92.5).21The L1 protein is the target of virus-neutralizing antibodies...
The HPV virion is a highly ordered structure whose major protein is L1 and when expressed in eukaryotic cells, results in the formation of VLPs that elicit HPV-neutralizing antibodies. Bivalent, quadrivalent, and nonavalent vaccines have been shown to be highly effective and have been licensed....
Providers may take the simple step of informing patients that their cancer is HPV-related and HPV vaccine is safe to increase the number of informed and empowered survivors.doi:10.1007/s00520-019-05035-1Zeena ShelalDalnim ChoDiana L. Urbauer...
不建议在怀孕后之前接种HPV疫苗。如果在怀孕期间无意中接种疫苗,则无需干预。 NO.5 带状疱疹疫苗/VZV 常规接种≥50岁:无论既往带状疱疹疫苗史或带状疱疹疫苗活疫苗(ZVL、Zostavax)疫苗接种史,建议间隔2-6个月接种2剂重组带状疱疹疫苗(RZV、Shingrix),最短间隔4周。如果接种过早,需要保证最短间隔后再次接种1剂。
In HPV-associated squamous cell carcinoma of the head and neck, TREG cells have been observed to have both positive and negative prognostic associations depending on the anatomical site (reviewed previously [160]), supporting the notion that the local and tissue-specific immune context can skew ...
F. HPV vaccine hesitancy among parents in Italy: a cross-sectional study. Hum. Vaccin. Immunother. 16, 2744–2751 (2020). Article Google Scholar Dubé, E. et al. Overview of knowledge, attitudes, beliefs, vaccine hesitancy and vaccine acceptance among mothers of infants in Quebec, Canada....
Vaccine hesitancy (VH) is considered a top-10 global health threat. The concept of VH has been described and applied inconsistently. This systematic review aims to clarify VH by analysing how it is operationalized. We searched PubMed, Embase and PsycINFO
A Phase II, Prospective, Randomized, Multicenter, Open-Label Study of GX-188E, an HPV DNA Vaccine, in Patients with Cervical Intraepithelial Neoplasia 3doi:10.1158/1078-0432.CCR-19-1513Youn Jin ChoiSoo Young HurTae Jin KimSung Ran Hong...
5.1. Parental agency among those consenting to HPV vaccines As the above findings suggest, these strategic tactics empowered parents to be agents in their decisions. First, the Vietnamese American parents became well-informed about the current vaccine debates from their social networks. The importance...
Related to β-thalassemia and sickle cell disease a self-inactivating lentivirus vector (HPV569) containing the β-globin gene (β(A-T87Q)-globin was modified (BB305) for enhanced virus titers and improved transduction efficacy [71]. Sustained therapeutic efficacy was achieved in β-thalassemic ...