A2 antigen with saponin in Brazil has efficiently prevented the development of active disease state in dogs preexposed to the parasite (Grimaldi et al., 2017). As, of these, few reach clinical trials, but there remains a significant gap towards the development of commercial vaccine for human ...
In dogs, the frenzy associated with intense pruritus and paralysis of the jaws and pharynx, accompanied by drooling of saliva and plaintive howling, simulates true rabies; however, there is no tendency for dogs to attack other animals. In cats, the disease may progress so rapidly that frenzy...
RABORAL V-RG has also been used to control wildlife rabies in Israel for more than a decade. This paper: (1) reviews the development and historical use of RABORAL V-RG; (2) highlights wildlife rabies control programs using the vaccine in multiple species and countries; and (3) discusses...
We chose to use minipigs as a nonrodent species for toxicology tests with the StreptInCor candidate vaccine. Minipigs have been increasingly used in toxicological studies for safety assessment as an alternative to dogs and primates, especially in Canada, the European Community and the United States...
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Efforts to make vaccines against infectious diseases as well as immunotherapies for cancer, autoimmune diseases and allergy have utilized a variety of heterologous expression systems, including viral and bacterial vectors, as well as DNA and RNA constructs. This review explores the immunologic rationale ...
While further study and awareness campaigns to improve community acceptance may eventually enable the effective use of ORV for dogs, delays in the adoption of effective tools such as ORV enable the continued persistence of the rabies virus in dogs around the world and perpetuates otherwise ...