In the United States, ~100,000 patients are hospitalized annually for cardiogenic shock with 27–51% mortality. Similarly, ~356,000 patients develop out-of-hospital cardiac arrests (OHCA) annually with 90% mortality. In the last few decades, several acut
in increased organ support-free days [134,135,137,138]. However, therapeutic heparin dose did not reveal significant advantages regarding in-hospital mortality or hospitalization length, but was associated with a slightly elevated risk of major bleeding [135]. In patients admitted to ICU without su...