There are comments on PubPeer for publication: Long non-coding RNA USP30-AS1 aggravates the malignant progression of cervical cancer by sequestering microRNA-299-3p and thereby overexpressing PTP4A1 (2021)
Notably, pro-inflammatory stimuli, including lipopolysaccharide (LPS) and tumor necrosis factor-α (TNF-α), were found to upregulate the expression of USP30-AS1. Functional assays demonstrated that the knockdown of USP30-AS1 resulted in increased degradation of IκBα protein and enhanced NF-κB...
we utilized the bioinformatics technology to study the expression of USP30-AS1 in AML. As shown in Fig.1A1, among a variety of cancers, USP30-AS1 has the most up-regulated expression in DLBC (Lymphoid Neoplasm Diffuse Large B cell Lymphoma) and LAML (Acute Myeloid Leukemia)...
USP30-AS1 is an interferon-stimulated gene, and the induction of USP30-AS1 can be achieved by JAK-STAT mediated signaling activation. The immune regulation of USP30-AS1 is independent of its proximal protein-coding gene USP30. In IAV infection, deletion of USP...
The results revealed a significant positive correlation of USP30-AS1 expression with the infiltration of immune cells such as Th1 cells, TFH, CD8 T cells, B cells, antigen-presenting dendritic cells (aDC), and plasmacytoid dendritic cells (pDC) in ovarian cancer specimens. These findings provide...
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cellsNingchao Wang a bJiao Li cQilei Xin a dNaihan Xu a b d
USP30-AS1ELFN1-AS1GAS8-AS1SNHG11Breast cancer is a widely prevalent and life-threatening malignancy that affects women worldwide. The identification of novel molecular markers associated with tumor progression is highly important for enhancing early detection, tailoring treatment approaches, and ...
USP30-AS1 suppressed the progression of colon cancer through modulating miR-765.doi:10.1186/s12957-022-02529-xChengren.LiDepartment of Anorectal Surgery, Weifang People's Hospital, No.151, Guangwen Street, Weifang, 261000, Shandong, China.Xu.Liang...