More recent trials have evaluated whether other treatment regimens, including lower doses or shorter durations of isoniazid in combination with other medications, may be associated with lower risk of hepatotoxicity. Meta-analysis of 3 trials (n = 7339) that compared isoniazid vs rifampin found ...
In 2020, the US Food and Drug Administration (FDA) issued a warning: …even when taken at recommended dosages, [benzodiazepine] use can lead to misuse, abuse, and addiction. Abuse and misuse can result in overdose or death, especially when benzodiazepines are combined with other medicines, su...
Surveys are a crucial tool for understanding public opinion and behaviour, and their accuracy depends on maintaining statistical representativeness of their target populations by minimizing biases from all sources. Increasing data size shrinks confidence intervals but magnifies the effect of survey bias: an...
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although smoking remains the most common route of administration (Hall et al, 2016), newly popular routes of administration offer even higher THC doses (Hall et al, 2016). These include edibles, vaping (inhaled vapor of heated e-liquids analogous to e-cigarettes), and dabbing (inhaled vapor...
The drug has been around since the 1940s and is known for being generally safe and well-tolerated in mild to moderate doses, although it can be toxic in high doses. It has been used to treat malaria, in addition to some autoimmune disorders. It is available as a generic, which means...
Note that the in situ heart activity recordings were made in the absence of additional phenanthrene doses and thus the measurements represent the effect of the 15-day phenanthrene exposure period on cardiac electrical activity. Monophasic action potentials (MAPs) and electrocardiograms (ECGs) were ...
However, the Trump administration agreed in July to buy at least $1.95 billion worth of a Pfizer vaccine, at least 100 million doses, if Pfizer does get a vaccine authorized by the Food and Drug Administration. Three experts told CNN that this purchase promise may have played a...
However, the Trump administration agreed in July to buy at least $1.95 billion worth of a Pfizer vaccine, at least 100 million doses, if Pfizer does get a vaccine authorized by the Food and Drug Administration. Three experts told CNN that this purchase promise may have played a...
The agencies are recommending that states do the same, but it will be up to the individual states to make that decision because they are given a separate allocation of doses. The pause happened because this type of blood clot is not listed on the list of potential adverse side effects th...