11,12 PAX2 is expressed in the metanephros and in cell lineages that are forming nephrons and also in those that are destined to differentiate into the ureter, renal pelvis, and branching collecting duct system. The ablation of a single PAX2 allele in knockout mice causes impaired...
FIGURE 20.2.(A) Hematoxylin- and eosin-labeled section of the bladder wall from a sheep. The mucosa consists of the thin, densely labeled urothelium and the lighter suburothelium. Detrusor smooth muscle s shown in pink; a large vein is shown bottom left. (B) Diagram showing the component...
FIG. 1B is a diagram that illustrates example linkage analysis that identifies five linked regions of the genome, according to an embodiment. The horizontal axis 112 indicates genetic distance across the genome, organized into the 22 chromosomes. The lengths of the labeled chromosomes represent the...
Alternatively, the limited overlap of differentially expressed miRNAs in kidney and urine might come from their restricted expression in certain nephron segments. To determine if exo-miRs (miR-16-5p, miR-24-3p, and miR-200c-3p) which were increased at the early injury state (day 1 after ...